OPTIMASI FORMULA MATRIKS TRANSDERMAL PENTAGAMAVUNON-0 DENGAN KOMBINASI POLIMER PVP K30 DAN HIDROKSIPROPIL METILSELULOSA MENGGUNAKAN SIMPLEX LATTICE DESIGN
| Main Authors: | , Beti Pudyastuti, , Dr. Akhmad Kharis Nugroho,M.Si., Apt. |
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| Format: | Thesis NonPeerReviewed |
| Terbitan: |
[Yogyakarta] : Universitas Gadjah Mada
, 2014
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| Subjects: | |
| Online Access: |
https://repository.ugm.ac.id/133197/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=73757 |
Daftar Isi:
- Transdermal delivery is one of the alternative delivery system to avoid the high intensity of first pass metabolism of pentagamavunon-0 (PGV-0) in peroral route. The purposes of this research were (1) to optimize the formula of PGV-0 transdermal matrix with a combination of PVP K30 and HPMC polymers