HUBUNGAN PAJANAN CO, SO2, NO2, UAP BESI DAN DEBU BESI DENGAN GANGGUAN FUNGSI PARU DAN KADAR IMUNOGLOBULIN SERUM PERAJIN LOGAM
| Main Authors: | , Husaini, SKM., M.Kes, , Prof. Dr. dr. KRT. Adi Heru Husodo, M.SC., D.CN., DLSHTM.,PKK |
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| Format: | Thesis NonPeerReviewed |
| Terbitan: |
[Yogyakarta] : Universitas Gadjah Mada
, 2014
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| Subjects: | |
| Online Access: |
https://repository.ugm.ac.id/131007/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=71443 |
Daftar Isi:
- Blacksmith centers which produce agricultural tools, household appliances, carpentry tools, souvenirs, wheels and other vessels are located in the sub District of Daha Utara and Daha Selatan, and District Hulu Sungai Selatan, South Kalimantan Province. The Blacksmiths during their works did not use personal protective equipment, they were always exposed to CO, SO2, NO2, metal fume and vapor, and other particles such as Diesel Exhaust Particles (DEP), and compounds resulting from the combustion process in a high temperature with results in lung disfunction (restrictive, obstructive and mixed), and the total IgE and total IgG levels. The objective of the investigation was to assess the correlation between exposure of CO, SO2, NO2, metal fume and vapor with lung disfunction (restrictive, obstructive and mixed), and the total IgE and total IgG levels. The study was analytic observational, and cross sectional design conducted in the sub Districts of Daha Utara and Daha Selatan. Blood sampling, measuring of CO, SO2, NO2 gases, metal fume and vapor, and Forced Vital Capacity (FVC), Forced Expiratory Volume1 (FEV1) and Mixed (FVC+FEV1) were conducted at Kandangan hospital, and Balai Hiperkes and keselamatan Kerja South Kalimantan Province, respectively. Whereas determination of total IgE and total IgG levels was carried out at Prodia laboratory Jakarta. The population of studies was the entire blacksmiths in sub districts of Daha Utara and Daha Selatan. The sampling procedure was based on purposive sampling predefined by inclusion and exclusion criteria with a sample of 38 units and 38 blacksmiths. Result were analyzed observational, and cross sectional design using Pearson correlation test, logistic regression, and test of Partial Least Square (PLS). Pearson correlation test showed a significant correlation exists due to exposure of CO, NO2, and metal fume. This was indicated by the FVC with p:< 0.05, although SO2 and metal fume was not significant. The results of logistic regression showed: (1) a significant correlation due to exposure of CO, SO2, NO2, metal fume, and vapor indicated by the FEV1 with p:< 0.05