SENSITIVITAS Escherichia coli PENGHASIL EXTENDED SPECTRUM BETA LACTAMASE (ESBL) TERHADAP ANTIBIOTIK GOLONGAN PENISILIN DARI ISOLAT KLINIS KOLEKSI BAGIAN MIKROBIOLOGI FK UGM PERIODE APRIL � SEPTEMBER 2013

Main Authors: , GLADIAN YANURISKA, , dr. Nurrokhman, M.Si
Format: Thesis NonPeerReviewed
Terbitan: [Yogyakarta] : Universitas Gadjah Mada , 2014
Subjects:
ETD
Online Access: https://repository.ugm.ac.id/127946/
http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=68266
ctrlnum 127946
fullrecord <?xml version="1.0"?> <dc schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"><relation>https://repository.ugm.ac.id/127946/</relation><title>SENSITIVITAS Escherichia coli PENGHASIL EXTENDED SPECTRUM BETA LACTAMASE (ESBL) TERHADAP ANTIBIOTIK GOLONGAN PENISILIN DARI ISOLAT KLINIS KOLEKSI BAGIAN MIKROBIOLOGI FK UGM PERIODE APRIL &#xE2;&#xFFFD;&#xFFFD; SEPTEMBER 2013</title><creator>, GLADIAN YANURISKA</creator><creator>, dr. Nurrokhman, M.Si</creator><subject>ETD</subject><description>Background : Infectious disease is one of biggest problem in Indonesia and even in the world. One of bacteria that cause a lot of infection is E. coli. Infection that caused by E. coli are diarrhea and urinary tract infection. According to various researches, using the &#xCE;&#xB2;-lactam antibiotics especially penicillin group had been reported resistant to this bacteria. The general mechanism of resistant is ESBL production by bacteria. Objective : This study was design to determine sensitivity of ESBL producing isolates of E. coli toward penicillin from clinical specimens at Microbiology Departement in Faculty of Medicine Gadjah Mada University. Methods : This study used descriptive method. Screening Test from CLSI 2012 and Mast Group Test&#xC2;&#xAE; were used to screening ESBL production. Kirby Bauer method was used for antibiotic susceptibility testing. Results : From 25 clinical samples, 7 from these were produced ESBL (28%). Result of susceptibility test to antibiotic penicillin group showed E. coli produced ESBL 100% resistant to penicillin G and ampicilin, 71,4% to amoxicillin and 85,7% to ticarcillin. While E. coli non ESBL 100% resistant to penicillin G, 88,5% to ampicillin, 77,8% to amoxicillin and ticarcillin. Conclusion : Penicillin group are resistant against E. coli.</description><publisher>[Yogyakarta] : Universitas Gadjah Mada</publisher><date>2014</date><type>Thesis:Thesis</type><type>PeerReview:NonPeerReviewed</type><identifier> , GLADIAN YANURISKA and , dr. Nurrokhman, M.Si (2014) SENSITIVITAS Escherichia coli PENGHASIL EXTENDED SPECTRUM BETA LACTAMASE (ESBL) TERHADAP ANTIBIOTIK GOLONGAN PENISILIN DARI ISOLAT KLINIS KOLEKSI BAGIAN MIKROBIOLOGI FK UGM PERIODE APRIL &#xE2;&#xFFFD;&#xFFFD; SEPTEMBER 2013. UNSPECIFIED thesis, UNSPECIFIED. </identifier><relation>http://etd.ugm.ac.id/index.php?mod=penelitian_detail&amp;sub=PenelitianDetail&amp;act=view&amp;typ=html&amp;buku_id=68266</relation><recordID>127946</recordID></dc>
format Thesis:Thesis
Thesis
PeerReview:NonPeerReviewed
PeerReview
author , GLADIAN YANURISKA
, dr. Nurrokhman, M.Si
title SENSITIVITAS Escherichia coli PENGHASIL EXTENDED SPECTRUM BETA LACTAMASE (ESBL) TERHADAP ANTIBIOTIK GOLONGAN PENISILIN DARI ISOLAT KLINIS KOLEKSI BAGIAN MIKROBIOLOGI FK UGM PERIODE APRIL � SEPTEMBER 2013
publisher [Yogyakarta] : Universitas Gadjah Mada
publishDate 2014
topic ETD
url https://repository.ugm.ac.id/127946/
http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=68266
contents Background : Infectious disease is one of biggest problem in Indonesia and even in the world. One of bacteria that cause a lot of infection is E. coli. Infection that caused by E. coli are diarrhea and urinary tract infection. According to various researches, using the Î2-lactam antibiotics especially penicillin group had been reported resistant to this bacteria. The general mechanism of resistant is ESBL production by bacteria. Objective : This study was design to determine sensitivity of ESBL producing isolates of E. coli toward penicillin from clinical specimens at Microbiology Departement in Faculty of Medicine Gadjah Mada University. Methods : This study used descriptive method. Screening Test from CLSI 2012 and Mast Group Test® were used to screening ESBL production. Kirby Bauer method was used for antibiotic susceptibility testing. Results : From 25 clinical samples, 7 from these were produced ESBL (28%). Result of susceptibility test to antibiotic penicillin group showed E. coli produced ESBL 100% resistant to penicillin G and ampicilin, 71,4% to amoxicillin and 85,7% to ticarcillin. While E. coli non ESBL 100% resistant to penicillin G, 88,5% to ampicillin, 77,8% to amoxicillin and ticarcillin. Conclusion : Penicillin group are resistant against E. coli.
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first_indexed 2016-09-14T18:33:07Z
last_indexed 2016-09-22T21:47:12Z
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