HUBUNGAN KETEPATAN PREPARASI DAN PEMBERIAN OBAT INTRAVENA VESICANT DENGAN KEJADIAN PLEBITIS

Main Authors: , Kardhina Apryliani, , Prof. Dr. Suwaldi M.,M.Sc., Apt.
Format: Thesis NonPeerReviewed
Terbitan: [Yogyakarta] : Universitas Gadjah Mada , 2013
Subjects:
ETD
Online Access: https://repository.ugm.ac.id/126085/
http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=66276
Daftar Isi:
  • Intravenous medication administration is widely performed in the hospitals. Vesicant drugs have the potential to cause tissue damage including phlebitis. Phlebitis can be avoided by appropriate preparation and admininistration. The aim of this study was to investigate correlation of appropriate prepraration and administration of vesicant drugs and phlebitis effect. Cross sectional study design was carried out using prospective observation of preparing, administering intravenous medications and phlebitis effect in Intensive Care Unit of Panembahan Senopati Hospital Bantul. Five aspects of preparation and four aspects of administration were assessed and presented descriptively. The result of assessment of preparation and administration aspects which have potential effects of phlebitis were presented as patientâ��s score. Phlebitis was categorized by dichotomous scale in each patient respectively. Correlation analysis of SPSS 15.0 program was used for analysis the data. Nine non-antineoplastic vesicant drugs (i.e., dopamine, dobutamine, amiodarone, diazepam, norepinephrine, vancomycin, aminophylline, calcium glukonate and mannitol) for 28 patients were observed. The number of appropriate preparations of: aseptic technique preparations observed were 34 (100%), proper labelling observed were 26 (78,8%), final checking observed were 0%, type of diluent observed were 31 (100%), and volume of diluent observed were 25 (80,6%). The number of appropriate administration of: aseptic technique administration observed were 34 (100%), duration of administration observed were 28 (82,35%), rate of administration observed were 30 (88,23%), and drug compatibility observed were 30 (88,23%). Phlebitis effects occured in 4 patient (80%) who were given the vesicant drugs. Correlation analysis showed that compatibility aspect have significant correlation with phlebitis (p=0,027). Standard operational procedures of preparation and administration must be improved, the role of pharmacist in compatibility of intravenous drugs is required.