UJI SKRINING NYERI NEUROPATIK SERABUT SARAF KECIL UNTUK STADIUM AWAL INFEKSI HIV PADA NARAPIDANA PEMAKAI NAPZA SUNTIK
| Main Authors: | , Yusak Mangara Tua Siahaan, dr., , Prof. dr. Lucas Meliala, Sp.S(K), Sp.KJ |
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| Format: | Thesis NonPeerReviewed |
| Terbitan: |
[Yogyakarta] : Universitas Gadjah Mada
, 2013
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| Subjects: | |
| Online Access: |
https://repository.ugm.ac.id/125125/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=65290 |
Daftar Isi:
- Background: With regard to increasing HIV/AIDS cases, it is crucial to detect HIV infection on early stage, especially in high risk population such as intravenous drug users. One of the most common clinical manifestations of HIV infection is pain. The prompt detection of small fiber neuropathic pain may establish a working diagnosis immediately. Therefore, proper treatment can be started right away so that may lowering possible mortality and morbidity in people with HIV. Objective: The objective of this study is to find the accuracy of pain symptoms as screening test for HIV infection in people with intravenous drug users. Method: This was a cross-sectional study conducted from June 2010 to November 2010 in Banten & West Java Penitentiary, Indonesia. A number of ninety people met the inclusion criteria: age 15-40 years old, intravenous drug user, not yet known HIV status, and reported pain complaint. Anamnesis of the pain complaints and HIV RAPID test were performed. The numbers of intradermal nerve fibers were counted on skin tissue biopsy sections stained with anti PGP 9.5 antibody. Data management was done with EpiData Program and analyzed using SPSS 19.0 using Pearson Chi-Square and Mann Whitney test at 95% confident interval. Result: We found only 24 people (26.7%) with HIV infection. Hyperalgesia is the highest percentage type of pain reported by the subject (7.8%). On the contrary, allodynia is felt by only 1 (1.1%) subject. Forty three (47.8%) subjects did have low density of epidermal nerve fibers but they are not related to the positive HIV test. HIV-associated pain sensitivity test results range from 4.17% to the highest 27.14%. Conclusion: The sensitivity of each type of pain toward HIV (+) test result is very. low. Pain is not associated with low density of intraepidermal nerve fibre. HIV (+) test result is not associated with low density of intraepidermal nerve.