ANALISIS DISTRIBUSI DOSIS RADIASI PADA TERAPI KANKER PAYUDARA DENGAN BORON NEUTRON CAPTURE THERAPY (BNCT) MENGGUNAKAN MCNP5
| Main Authors: | , DIAN NOVIANTI, , Dr. Ir. Andang Widi Harto, M.T. |
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| Format: | Thesis NonPeerReviewed |
| Terbitan: |
[Yogyakarta] : Universitas Gadjah Mada
, 2013
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| Subjects: | |
| Online Access: |
https://repository.ugm.ac.id/124260/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=64380 |
Daftar Isi:
- Boron Neutron Capture Therapy (BNCT) is therapy that utilizes the interaction of neutron with boron-10 to kill cancer cells. Boron Neutron Capture Therapy (BNCT) is currently being developed for the treatment of HER-2+ breast cancer. HER-2+ breast cancer is resistant and have a chance of recurrence. The purpose of this study is to research about dose distribution for treatment HER-2+ breast cancer. This study used MCNP 5 simulation program to calculate the thermal neutron flux on the cancer and the health tissue so absorbed dose can be calculated. Concentration of boron-10 was varied into 20, 30, 40, 50, 60 and 70 �g/g, while variations on irradiation technique were en face technique and lateral technique. The result showed dose rate on the tumor volume increased and shorter irradiation times with increasing concentration of boron-10. So skin dose and lungs dose were reduced. En face technique gives the treatment time is shorter than lateral technique. Dose distribution in the concentration of boron-10 70 �g/g by en face technique received by skin, CTV, cancer, health tissue and lungs, respectively, 0.86 Gy