KORELASI ANTARA KADAR VITAMIN E DALAM SERUM DENGAN DERAJAT KEPARAHAN AKNE VULGARIS DI YOGYAKARTA
| Main Authors: | , HENRY NUR KUSUMA WARDANI, , dr. Kristiana Etnawati, MPH, Sp.KK (K) |
|---|---|
| Format: | Thesis NonPeerReviewed |
| Terbitan: |
[Yogyakarta] : Universitas Gadjah Mada
, 2013
|
| Subjects: | |
| Online Access: |
https://repository.ugm.ac.id/123105/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=63216 |
Daftar Isi:
- Background: Acne vulgaris is a skin disease that has always been a problem for adolescents and young adults. The pathogenesis of acne involves the increased excretion of sebum, hyperkeratosis of duct pilosebaceus, Propionibacterium acnes colonization in the duct and the release of inflammatory mediators and the immune response. Propionibacterium acnes produce inflammatory mediators, one of which is a chemotactic factors. Chemotactic factors that will lead to the accumulation of neutrophils that will produce free radicals. Free radicals can damage Propionibacterium acnes and the surrounding normal tissue. Required to inhibit the breakdown of antioxidants. The main antioxidants contained skin is vitamin E. Objective: To find a correlation between serum levels of vitamin E in various degress of severity of acne vulgaris Methods: This research used cross-sectional method involving 51 respondents acne vulgaris patients with various degrees of severity of acne were included in the inclusion criteria. Vitamin E levels in serum were measured using the method of R.G Martinek. Researcher using Pearson correlation analysis test and ANOVA to analyze the data. The results: -0.202 correlation value (r = -0.202) between serum levels of vitamin E in the severity of acne. This study was not statistically significant (p = 0.155, p> 0,05). There was no significant difference in the levels of vitamin E on the degree of acne severity as indicated by the significance of the 0.355 one way ANOVA test. Conclusion: There was no correlation between serum levels of vitamin E in the degree of severity of acne vulgaris.