PERBANDINGAN KUALITAS HIDUP PENDERITA KANKER SERVIKS YANG DIBERIKAN KEMORADIASI BERBASIS CISPLATIN DENGAN CISPLATIN TUNGGAL DI RSUP DR SARDJITO YOGYAKARTA
| Main Authors: | , IRFAN MULYANA MUSTOFA, , dr. H. Heru Pradjatmo, M.Kes, SpOG(K) |
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| Format: | Thesis NonPeerReviewed |
| Terbitan: |
[Yogyakarta] : Universitas Gadjah Mada
, 2013
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| Subjects: | |
| Online Access: |
https://repository.ugm.ac.id/119734/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=59737 |
Daftar Isi:
- Objective: Comparing the quality of life in patients with cervical cancer given Cisplatin-based versus single Cisplatin chemoradiation and risk factors that influencing. Material dan Method: A retrospective cohort study design in 146 patients with cervical cancer. Seventy three patients in each group have completed 1 series of weekly Cisplatin + 5-FU or 3 weekly Cisplatin chemoradiation at Sardjito Hospital Yogyakarta. For assessing the quality of life, the author used EORTC QLQ-C30 and QLQ-CX24. Data distribution was analytically tested by Kolmogorov-Smirnov. Categorical data were tested with Chi-Square, while continous data with Mann-Whitney test. Multivariable analysis used logistic regression. Result: The results of Mann-Whitney test found significant mean difference almost in all items, except for item of diarrhea in QlQ-C30 and sexual/vaginal function item in QLQ-CX24. The mean value of quality of life in Cisplatin + 5- FU is higher than single Cisplatin (72.60 + 16.98 vs 62.22 + 16.73). We found relationship of high quality of life in Cisplatin + 5-FU chemoradiation 1.73 times than single Cisplatin (RR 1.73