KONDISI LARING SAAT INTUBASI PADA 60 DETIK SETELAH PEMBERIAN ROKURONIUM 0,6 MG/KGBB INTRAVENA PADA GENERAL ANESTHESIA (Setelah mendapat Fentanil 2 mcg/kgbb dan Induksi Propofol 2 mg/kgbb)

Main Authors: , HELDA LIZA MURYA KOTO, , Dr. Bhirowo Yudo P, SpAn.KAKV
Format: Thesis NonPeerReviewed
Terbitan: [Yogyakarta] : Universitas Gadjah Mada , 2013
Subjects:
ETD
Online Access: https://repository.ugm.ac.id/118540/
http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=58515
Daftar Isi:
  • Background: Rocuronium is a nondepolarizing muscle relaxant drug that having a rapid onset and minimal side effects. Intravenously rocuronium doses of 0,6 mg/kgbw (2 x ED95) facilitate a good intubation condition within 1 minute in most of patient. The ideal intubation condition are when larynx condition based on Kreig score at 3-4 (excellent) and TOF value in AP muscle at 100%. The aim of this study is to assess the condition of the larynx and TOF values during the intubations at 60 seconds after administration rocuronium 0.6 mg / kg bw intravenously. Method: A prospective observational study was conducted with 88 ASA I-II patients undergoing general anesthesia with orotracheal intubation and predicted no difficulty for intubation. Sixty second after administration of rocuronium 0.6 mg / kgbw, the condition of the larynx during intubation was assesed with score of Kreig, the value of TOF on adductor pollicis muscle, and the hemodynamic changes between 1 minute before,compare with 1 and 3 minute after intubation. Result : The condition of larynx at 60 s after administration of rocuronium 0,6 mg/kg bw was â��excellentâ�� in 87 patient (98,9%), and â��goodâ�� in 1 patient (1,1%). While the TOF value at 60 s after administration of rocuronium 0,6 mg/kg bw was 75% in 3 patient (3,4%), 80% in 40 patient (45,5%), 90% in 42 patient (47,7%) and 100% in 3 patient (3,4%). In this study, there was no significant difference in the mean of systolic blood pressure, diastolic blood pressure, mean arterial pressure, and heart rate between 1 minute before intubation and 1 minute and 3 minutes after intubation (p> 0.05). Conclusion : The condition of larynx at intubation at 60 s after administration of rocuronium was â��excellentâ�� at 98,9% and â��goodâ�� at 1,1%. The TOF value in â��excellentâ�� patient was 75% in 3 patient (3,4%), 80% in 39 patient (45,5%), 90% in 42 patient (47,7%) and 100% in 3 patient (3,4%), while TOF value in â��goodâ�� patient was 80% in 1 patient.