Uji Efek Stimulansia Infusa Rimpang Temulawak (Curcuma xanthorrhiza Roxb.) Pada Mencit Jantan Galur Swiss
| Main Author: | Tary, Neni Lugki Nian |
|---|---|
| Format: | Karya Ilmiah NonPeerReviewed application/pdf |
| Bahasa: | eng |
| Terbitan: |
, 2015
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| Subjects: | |
| Online Access: |
http://eprints.ums.ac.id/35937/1/NASKAH%20PUBLIKASI.pdf http://eprints.ums.ac.id/35937/2/COVER%2BHALAMAN%20DEPAN.pdf http://eprints.ums.ac.id/35937/4/BAB%201.pdf http://eprints.ums.ac.id/35937/6/BAB%202.pdf http://eprints.ums.ac.id/35937/8/BAB%203.pdf http://eprints.ums.ac.id/35937/9/BAB%204.pdf http://eprints.ums.ac.id/35937/11/DAFTAR%20PUSTAKA.pdf http://eprints.ums.ac.id/35937/13/LAMPIRAN.pdf http://eprints.ums.ac.id/35937/14/SURAT%20PERNYATAAN%20PUBLIKASI.pdf http://eprints.ums.ac.id/35937/ |
Daftar Isi:
- The use of plants that efficacious as a medicine in the prevention of health problems known to Indonesian people long since passed down from generation to generation. Zingiberaceae family empirically used as a stimulant, one of which is ginger, therefore it is necessary to do research on the effects of curcuma rhizome as a stimulant. Research conducted using experimental methods pre-test and post-test with control design. Twentyfive male mice Swiss strain used as experimental animals, which are divided into five groups, positive control (caffeine 100 mg/kgBW), negative control (distilled water 0,5 mL/20 gBW), infusion of curcuma dose I (2.5 g/kgBW), dose II (5 g/kgBW), and dose III (10 g/kgBW) respectively. Animal experiments tested using methods Natatory Exhaustion and treated with oral route. The resulting effects of stimulant tired calculated the time difference before and after treatment. The data obtained were analyzed using non-parametric statistical tests using Kruskal Wallis and Mann Whitney with a 95% confidence level. Infuse curcuma rhizome have the stimulant effect, the effect obtained by increasing along with the increase in dose. At doses of 2.5 g/kgBW, 5 g/kgBW, and 10 g/kgBW be able to provide a stimulant effect respectively by 2.82 ± 1,02 minutes, 3.71 minutes and 4.94 minutes. Stimulant effect dose II and III have a greater effect than the positive control (p<0,05), the dose I had similar effect compare with control positive (p>0,05).