EFEK PEMBERIAN GLUKOMANAN UMBI PORANG (Amorphophallus oncophyllus Prain ex Hook. f.) TERHADAP KADAR KOLESTEROL TOTAL DARAH TIKUS YANG DIBERI DIET TINGGI LEMAK
| Main Authors: | Nugraheni, Bekti, Cahyani, Intan Martha, Herlyanti, Kyky |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
e-Publikasi Ilmiah Fakultas Farmasi Unwahas Semarang
, 2015
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| Online Access: |
http://publikasiilmiah.unwahas.ac.id/index.php/ilmuFarmasidanklinik/article/view/1366 http://publikasiilmiah.unwahas.ac.id/index.php/ilmuFarmasidanklinik/article/view/1366/1471 |
Daftar Isi:
- ABSTRACTIndonesia is a country with abundant natural resources, one of which tubers. Plants types of tubers that have a lot of glucomannan content of the tuber porang. Glucomannan is used as a diet in patients with hypercholesterolemia. Glucomannan from tubers porang (Amorphophallus oncophyllus Prain ex Hook.f.) serves as a water-soluble fiber and have a low calorie.The purpose of this study was to determine the effect of glucomannan tuber porang (Amorphophallus oncophyllus Prain ex Hook.f.) to decrease total blood cholesterol mice fed a high-fat diet and to determine what dose of glucomannan tubers porang most effective for lowering blood cholesterol.The treatment in this study is glucomannan flour dose of 25 mg / kg; 50 mg / kg; and 100 mg / kg. The population in this study was a white rat (Rattus norvegicus) males aged 2-3 months with BB ± 200 g.Giving glucomannan porang tubers dose 25 mg / kg; 50 mg / kg; and 100 mg / kg give effect to the reduction in total blood cholesterol mice fed a high-fat diet. Effective dose for lowering total cholesterol levels of mice that is 50 mg / kg.Keywords: glucomannan tuber porang (Amorphophallus oncophyllus Prain ex Hook.f.), total cholesterol.