The Correlation between Tumor Necrosis Factor Alpha Exp ression and The Degree of Bone Destruction in Chronic Suppurative Otitis Media with Cholesteatoma

Main Authors: Fransiska, Fransiska, Artono, Artono, Purnami, Nyilo
Format: Proceeding PeerReviewed application/pdf
Bahasa: eng
Terbitan: , 2018
Subjects:
Online Access: http://repository.ubaya.ac.id/38830/
Daftar Isi:
  • Background: Choles eatoma is an important pathogen tissue causing bone destruction, therefore serious complications may happen. Tumor necrosis factory. is a main cytokine involved in bone destruction. Objective: To find out the correlation betv1een the expression of TNF-u. and the degree of bone destruction in CSOM cholesteatoma. Method: This is an analitycal observational study with cross section al design. Bone destruction was determined by otologist during surgery. All tissues were examined for TN F-a expression using rabbit anti TNF-u. polyclonal antibody.