Oxytocin formulations and uses thereof
| Main Authors: | Amorij, Jean-Pierre , Avanti, Christina, Frijlink, Henderik W. , Hinrichs, Wouter Leonardus Joseph |
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| Format: | Patent NonPeerReviewed application/pdf |
| Terbitan: |
, 2012
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| Subjects: | |
| Online Access: |
http://repository.ubaya.ac.id/31294/1/Oxytocin%20formulations%20and%20uses%20thereof.pdf https://www.google.com/patents/EP2326341B1 http://repository.ubaya.ac.id/31294/ |
Daftar Isi:
- The present invention relates to the field of preventive and therapeutic medicine, in particular to peptide formulations. Provided is a p H-buffered aqueous formulation comprising oxytocin, vasopressin or an analogue thereof and at least one non-toxic source of divalent metal ions in a concentration of at least 2 m M, and the use of the formulation for the manufacture of a medicament for therapeutic and/or prophylactic treatments. Also provided is a method for treating or preventing haemorrhage in a subject in need thereof, comprising administering to said subject an effective dosage amount of an oxytocin formulation according to the invention. Further provided is a method for treating or preventing diabetes insipidus or vasodilatory shock in a subject in need thereof, comprising administering to said subject an effective dosage amount of a vasopressin formulation according to the invention.