HUBUNGAN PROFIL LIPID LOW-DENSITY LIPOPROTEIN PENDERITA OBESITAS TERHADAP KEJADIAN INFARK MIOKARD AKUT PADA PASIEN RUMAH SAKIT UMUM PUSAT PROF. DR. I.G.N.G. NGOERAH DENPASAR TAHUN 2016-2021
| Main Authors: | Priambodo, Abiyyuda Naufal, Muliani, Muliani, Yuliana, Yuliana, Karmaya, I Nyoman Mangku |
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| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Universitas Udayana
, 2023
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| Online Access: |
https://ojs.unud.ac.id/index.php/eum/article/view/95647 https://ojs.unud.ac.id/index.php/eum/article/view/95647/50718 |
Daftar Isi:
- Latar Belakang: Dewasa ini epidemi obesitas menjadi salah satu tantangan terbesar kesehatan global dan tidak terkecuali di Indonesia. Obesitas dapat meningkatkan risiko penyakit kardiovaskular melalui beberapa faktor risiko yang diantaranya adalah peningkatan kadar profil lipid meliputi kolesterol total, LDL, HDL, dan trigliserida. Profil lipid LDL memegang peranan penting dalam proses aterogenesis dan berpotensi menyebabkan infark miokard akut. Tujuan: Penelitian ini dilakukan dengan tujuan untuk menggambarkan karakteristik pasien obesitas dan melihat hubungan profil lipid LDL terhadap kejadian infark miokard akut pada pasien obesitas RSUP Prof. Dr. I.G.N.G. Ngoerah Denpasar tahun 2016 - 2021. Metode: Penelitian ini menggunakan desain observasional analitik dengan pendekatan potong lintang. Pengambilan sampel dilakukan dengan teknik random sampling dan didapatkan 141 data rekam medis pasien obesitas yang teregistrasi di instalasi rekam medis RSUP Prof. Dr. I.G.N.G. Ngoerah Denpasar dan telah memenuhi kriteria inklusi. Hasil: Hasil uji statistik menunjukkan rata-rata kadar profil lipid pasien obesitas meliputi kolesterol total (158,49 mg/dL), LDL (97,85 mg/dL), HDL (34,81 mg/dL), dan trigliserida (161,79 mg/dL). Hasil analisis chi-square menemukan nilai p ? 0,05 menunjukkan bahwa adanya hubungan signifikan antara profil lipid LDL terhadap kejadian infark miokard akut pasien obesitas RSUP Prof. Ngoerah Denpasar tahun 2016 - 2021. Simpulan: Terdapat hubungan signifikan antara profil lipid LDL terhadap kejadian infark miokard akut pasien obesitas RSUP Prof. Ngoerah Denpasar tahun 2016 - 2021. Kata kunci: Obesitas, Infark Miokard Akut, Profil Lipid, Low-Density Lipoprotein
- Background: These days the obesity epidemic is rapidly becoming the biggest global health challenge including in Indonesia. Obesity can increase the risk of cardiovascular disease through several risk factors, including increased lipid profile levels such as total cholesterol, LDL, HDL, and triglycerides. LDL lipid profile plays an important role in atherogenesis and can potentially cause acute myocardial infarction. Objective: This study was conducted with the aim of describing the characteristics of obese patients and seeing the relationship between LDL lipid profile and the incidence of acute myocardial infarction in obese patients at Prof. Dr. I.G.N.G. Ngoerah General Hospital Denpasar in 2016 - 2021. Method: This study used an analytic observational design with a cross-sectional approach. Sampling was carried out by random sampling technique and obtained 141 medical record data of obese patients who were registered at the medical record installation of Prof. Dr. I.G.N.G. Ngoerah Denpasar and met the inclusion criteria. Result: Statistical test results showed that the average lipid profile levels of obese patients included total cholesterol (158.49 mg/dL), LDL (97.85 mg/dL), HDL (34.81 mg/dL), and triglycerides (161.79 mg/dl). The results of the chi-square analysis is p-value ? 0.05 indicating that there was a significant relationship between the LDL lipid profile and the incidence of acute myocardial infarction in obese patients at Prof. Ngoerah hospital Denpasar 2016 - 2021. Conclusion: There was a significant relationship between LDL lipid profile and the incidence of acute myocardial infarction in obese patients at Prof. Ngoerah hospital Denpasar 2016 - 2021. Keywords: Obesity, Acute Myocardial Infarction, Lipid Profile, Low-Density Lipoprotein