GAMBARAN KARAKTERISTIK PASIEN ACUTE MYELOID LEUKEMIA DI RSUP SANGLAH DENPASAR TAHUN 2018
| Main Authors: | Cahya Wibawa, I Made Bagus, Subawa, A. A. Ngurah, Sutirta Yasa, I Wayan Putu, Mahartini, Ni Nyoman |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Universitas Udayana
, 2021
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| Online Access: |
https://ojs.unud.ac.id/index.php/eum/article/view/75007 https://ojs.unud.ac.id/index.php/eum/article/view/75007/40149 |
Daftar Isi:
- Acute Myeloid Leukemia (AML) merupakan salah satu keganasan hematologi dengan jumlah penderita terbanyak di dunia. Insiden AML meningkat setiap tahunnya secara global. Penelitian ini bertujuan mengetahui karakteristik pasien AML di Bagian Penyakit Dalam RSUP Sanglah Denpasar tahun 2018. Penelitian dilakukan dengan metode deskriptif menggunakan studi potong lintang. Penelitian dilaksanakan pada bulan Maret - September 2019. Sampel penelitian ini sebanyak 34 rekam medik pasien AML yang dirawat inap di RSUP Sanglah tahun 2018. Data dianalisis menggunakan perangkat lunak Microsoft Excel untuk mendapatkan karakteristik pasien AML berdasarkan usia, keluhan utama, jenis kelamin, kadar hemoglobin, jumlah leukosit, jumlah trombosit, persentase blast, dan diagnosis berdasarkan FAB. Hasil penelitian menunjukkan frekuensi tertinggi pasien AML diperoleh pada kelompok usia 41-60 tahun (35,29%) dan didominasi jenis kelamin laki-laki (58,82%). Keluhan utama tersering yang dialami adalah badan lemah (55,88%). Berdasarkan hasil pemeriksaan darah lengkap, kebanyakan pasien AML ditemukan mengalami anemia sedang dengan kadar hemoglobin 8-10 g/dL (58,82%), jumlah leukosit >50.000/mm3 atau hiperleukositosis (47,06%), dan trombositopenia grade IV dengan jumlah trombosit <25.000/mm3 (38,24%). Berdasarkan pemeriksaan sumsum tulang, frekuensi terbanyak ditemukan pada pasien AML dengan persentase sel blast 30-39% (38,24%) dan tipe AML M4 atau Acute Myelomonocytic Leukemia (44,12%). Hasil penelitian ini berguna untuk penelitian lanjutan karena dapat memberi gambaran tentang karakteristik pasien AML di RSUP Sanglah Bali tahun 2018. Perlu dilaksanakan penelitian lebih lanjut untuk mengetahui hubungan antar variabel. Kata Kunci: Acute Myeloid Leukemia, Gambaran Karakteristik
- Acute Myeloid Leukemia (AML) is the most frequent hematologic malignancy in the world. AML rates of incidence are globally increasing each years. This study aims to determine the characteristics of AML cases in RSUP Sanglah Internal Medicine Department in 2018. The study was conducted descriptively using cross-sectional studies. This study was done in March-September 2019. The sampels were 34 medical records of AML patients who were hospitalized at RSUP Sanglah in 2018. Data were analyzed with Microsoft Excel software to determine the characteristics of AML patients based on age, hemoglobin level, main complaint, sex, leukocyte count, thrombocyte count, blast percentage, and diagnosis based on FAB classification. Results showed that the highest frequency of AML found on age group 41-60 years old (35.29%) and were dominated by male (58.82%). The most frequent main complaint is fatigue (55.88%). Based on complete blood count, most AML patients were having moderate anemia with Hb level 8-10 g/dL (58.82%), hyperleukocytosis with leukocyte count >50.000/mm3 (47.06%), and grade IV thrombocytopenia with thrombocyte count <25.000/mm3 (38.24%). Based on bone marrow examination, the highest frequency found among AML patients with blast percentage 30-39% (38.24%) and AML type M4 or Acute Myelomonocytic Leukemia (44.12%). These findings are useful to provide the insight regarding the characteristic of AML patients at RSUP Sanglah Bali in the year of 2018. Further research is still needed to determine each variable correlation. Keywords: Acute Myeloid Leukemia, Characteristics