KARAKTERISTIK KLINIS DAN DIAGNOSIS SITOLOGI PASIEN DENGAN NODUL TIROID YANG DILAKUKAN PEMERIKSAAN FINE NEEDLE ASPIRATION BIOPSY (FNAB) DI INSTALASI PATOLOGI ANATOMI RSUP SANGLAH DENPASAR TAHUN 2015
| Main Authors: | Dado Armawan, I Gusti Putu, Ekawati, Ni Putu |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Universitas Udayana
, 2020
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| Online Access: |
https://ojs.unud.ac.id/index.php/eum/article/view/64055 https://ojs.unud.ac.id/index.php/eum/article/view/64055/36482 |
Daftar Isi:
- FNAB pada nodul tiroid bertujuan mengarahkan tatalaksana pasien dengan menyeleksi individu-individu yang dicurigai mengalami keganasan dari kelompok besar pasien dengan nodul jinak. Penelitian ini dilakukan untuk mengetahui karakteristik klinis dan diagnosis sitologi pasien nodul tiroid yang dilakukan pemeriksaan FNAB di instalasi patologi anatomi RSUP Sanglah Denpasar tahun 2015. Penelitian ini menggunakan metode penelitian deskriptif cross-sectional. Subjek penelitian diambil dari rekam medis pasien nodul tiroid yang ada di instalasi patologi anatomi RSUP Sanglah Denpasar periode Januari-Desember 2015. Data diambil secara total sampling. Dari 332 sampel didapatkan proporsi nodul tiroid pada perempuan sebesar 78% dan laki-laki 22%. Lebih sering terjadi pada rentang usia 40-49 tahun (31,9%) pada perempuan maupun laki-laki. Ukuran nodul <5cm lebih sering ditemukan (75,9%). Diagnosis klinis nodul tiroid yang paling sering ditemukan adalah goiter tiroid (53,9%). Sebanyak 284 sampel diagnosis tunggal FNAB dikelompokkan berdasarkan kriteria TBSRTC: I. Nondiagnostic atau tidak memuaskan (unsatisfactory) 1,8%; II. Jinak 59,5%; III. Atypia of undetermined significance atau lesi folikuler dari undetermined significance 0,4%; IV. Neoplasma folikuler atau curiga neoplasma folikuler 33,8%; V. Curiga keganasan 2,5%; dan VI. Ganas 2,1%. Sedangkan pada diagnosis jamak ditemukan neoplasma folikuler dan nodul koloid 46,2%; nodul koloid dan tiroiditis 23,1%; karsinoma papiler dan nodul koloid 15,4%; serta nodul koloid dan hiperplasia folikuler 15,4% dari 13 sampel. Kata kunci : karakteristik, sitologi, nodul tiroid
- FNAB assists in guiding the clinical management of patients with thyroid nodules by helping to select those individuals who are more likely to have a malignancy from the larger group of patients with benign nodules. This study was conducted to describe the clinical features and cytologic diagnosis of patients with thyroid nodules which performed Fine needle aspiration biopsy (FNAB) in Department of Anatomical and Pathology Sanglah Hospital, Denpasar in 2015 period. The study use descriptive cross-sectional design. The subjects were taken from the medical records of patients which performed Fine needle aspiration biopsy (FNAB) in Department of Anatomical and Pathology Sanglah Hospital, Denpasar during January to December 2015 period. Data taken by total sampling. The proportion of thyroid nodules in women by 78% and men 22%. Thyroid nodules are most in the age range 40-49 years (31.9%). Nodule size <5cm more often (75.9%). The most common clinical diagnosis was goitre (53.9%). From 284 samples of single FNAB diagnosis that can be grouped based on the criteria TBSRTC: I. Nondiagnostic or unsatisfactory 1.8%; II. Benign 59.5%; III. Atypia of undetermined significance or follicular lesion of undetermined significance 0.4%; IV. Follicular neoplasm or suspicious for a follicular neoplasms 33.8%; V. Suspicious for malignancy 2.5%; and VI. Malignant 2.1% of the overall sample. While in multiple diagnosis are found follicular neoplasms and colloid nodules 46.2%; colloid nodules and thyroiditis 23.1%; papillary carcinoma and colloid nodule 15.4%; as well as colloid nodules and follicular hyperplasia 15.4% of 13 sample. Keywords : characteristic, cytology, thyroid nodule