KARAKTERISTIK MANIFESTASI KLINIS PASIEN SISTEMIK LUPUS ERITEMATOSUS DI POLIKLINIK REMATOLOGI RSUP SANGLAH PERIODE JUNI – SEPTEMBER 2018
| Main Authors: | Angga P Darma, Nyoman, Anom Saturti, Tjokorda Istri, Kurniari, Pande Ketut |
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| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Universitas Udayana
, 2020
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| Online Access: |
https://ojs.unud.ac.id/index.php/eum/article/view/61063 https://ojs.unud.ac.id/index.php/eum/article/view/61063/35196 |
Daftar Isi:
- Systemic Lupus Erytmatosus (SLE) adalah penyakit autoimun yang melibatkan berbagai organ dengan manifestasi klinis bervariasi dari yang ringan sampai berat. Tingkat prevalensi SLE di dunia berkisar antara 20 sampai 70 per 100.000 penduduk. Kepala Badan Litbang Kesehatan Kementrian Kesehatan RI, dr. Dr. Trihono,MSc menyatakan bahwa di Indonesia, orang penderita lupus (ODAPUS) diperkirakan berjumlah 1,5 juta orang dengan 100.000 ODAPUS baru ditemukan setiap tahunnya. Penelitian ini bertujuan untuk mengetahui gambaran manifestasi klinis yang dialami oleh pasien SLE di Poliklinik Imun-Rematologi RSUP Sanglah Denpasar periode Juni – September 2018. Penelitian ini merupakan penelitian deskriptif retrospektif yang menggunakan data sekunder yaitu rekam medis pasien. Sampel penelitian adalah 56 pasien SLE yang dipilih secara random sampling. Hasil penelitian menunjukan bahwa dari 56 pasien mayoritas berada pada rentang usia 20-29 tahun yaitu sebanyak 24 pasien (42,85%). 51 pasen merupakan perempuan (91,07%). Manifestasi terbanyak yang dialami adalah fatigue ( 55,35%) diikuti demam (51,78%), nyeri sendi (44,64%), ruam malar (35,71%), Sindrom (33,93%), Fotosensitifitas (30,35%), Anemia (28,57%), rambut rontok (26,78%), gangguan pencernaan (23,21%), trombositopenia (16,07%), leukopenia ( 14,28%), xerostomia (14,28%), fenomena raynaud, serositis (7,14%), gangguan pernapasan (7,14%), gangguan neurologi (7,14%), dan ulser oral (3,57%). Kata Kunci : SLE, Manifestasi Klinis
- Systemic Lupus Erytmatosus (SLE) is an autoimmune disease involving various organs with clinical manifestations varying from mild to severe. The prevalence of SLE in the world ranges from 20 to 70 per 100,000 population. Head of the Health Research and Development Agency of the Indonesian Ministry of Health, dr. Dr. Trihono, MSc stated that in Indonesia, people with lupus (ODAPUS) are estimated at 1.5 million people with 100.000 new ODAPUSs found each year. This study aims to describe the clinical manifestations experienced by SLE patients in the Immun-Polyclinic of Sanglah Hospital Denpasar, June - September 2018. This study is a retrospective descriptive study that uses secondary data, namely the patient's medical record. The study sample was 56 SLE patients selected by random sampling. The results of the study showed that of 56 patients the majority were in the age range of 20-29 years as many as 24 patients (42.85%). 51 pasen are women (91.07%). The most manifestations experienced were fatigue (55.35%) followed by fever (51.78%), joint pain (44.64%), malar rash (35.71%), syndrome (33.93%), photosensitivity (30 , 35%), anemia (28.57%), hair loss (26.78%), digestive disorders (23.21%), thrombocytopenia (16.07%), leukopenia (14.28%), xerostomia (14 , 28%), raynaud phenomena, serositis (7.14%), respiratory disorders (7.14%), neurological disorders (7.14%), and oral ulcers (3.57%). Keywords : SLE, Clinical Manifestation