GAMBARAN KARAKTERISTIK PASIEN MIELOMA MULTIPEL DI RSUP SANGLAH PADA TAHUN 2014-2015

Main Authors: Mahasuarya Pinatih, I Gede Wahyu, Anggreni Rena, Ni Made Renny
Format: Article info application/pdf eJournal
Bahasa: eng
Terbitan: Universitas Udayana , 2020
Online Access: https://ojs.unud.ac.id/index.php/eum/article/view/60409
https://ojs.unud.ac.id/index.php/eum/article/view/60409/34990
Daftar Isi:
  • Mieloma multipel adalah keganasan sel plasma dalam sumsum tulang yang khas disertai lesi osteolitik dan terdapat protein monoklonal dalam serum serta urine. Angka kejadian mieloma multipel pada skala dunia diperkirakan sekitar 86.000 kasus per tahun. Untuk mengetahui data serta karakteristik pasien mieloma multipel di RSUP Sanglah Denpasar pada tahun 2014-2015, telah dilakukan penelitian deskriptif retrospektif. Populasi target penelitian ini adalah penderita multipel mieloma yang berobat dari tahun 2014 sampai tahun 2015 di RSUP Sanglah Denpasar. Dengan teknik total sampling didapatkan sampel sebanyak 23 orang dengan proporsi terbesar kelompok usia >50 tahun sebanyak 82,6%, jenis kelamin laki-laki sebanyak 65,2%, pekerjaan yakni petani sebanyak 10 orang. Pada kategori keluhan pasien hampir seluruh sampel memiliki keluhan lemas yaitu sebanyak 95,7%. Proporsi terbesar pada kategori temuan pemeriksaan fisik adalah anemia sebanyak 87%. Pada kategori temuan laboratorium didapatkan rerata leukosit sebesar 6,51 × 103/mm3 ± 2,864, trombosit sebesar 168,62 × 103/mm3 ± 121,232, dan urea sebesar 26,45 g/hari ± 32,268. Proporsi kadar hemoglobin terbesar adalah 8-9,9 g/dl sebanyak 39,1%, kadar kreatinin < 2 mg/dl sebanyak 82,6%, kadar serum kalsium < 10 mg/dl sebanyak 30,4%, dan jumlah sel plasma 30% - 70% sebanyak 52,2%. Proporsi terbesar pada kategori pengobatan adalah kemoterapi sebanyak 100% dan kondisi sewaktu pulang membaik sebesar 73,9%. Kata Kunci : Mieloma Multipel, Karakteristik Penderita, Sanglah
  • Multiple myeloma is cancer of blood cell that develops in the bone marrow, characterized by osteolitic lesion and monoclonal protein in the serum and urine. The incidence of multiple myeloma in all over the world is around 86.000 case per year. A descriptive retrospective was established to know about the characteristics of patient with multiple myeloma in RSUP Sanglah during 2014-2015. The target populations of this study are the patients who were suffering from multiple myeloma and hospitalized in RSUP Sanglah for period of 2014-2015. A total of 23 sample was found using total sampling technique with the biggest proportion of age >50 years with a percentage of 82.6%, the biggest proportion of gender is male with a percentage of 65.2%, the biggest proportion of occupation is farmer in total 10 persons. Almost all of the sample complained about weakness with a percentage of 95.7%. The biggest proportion of physical examination is anemic look with a percentage of 87%. The mean value of laboratory examination are leukocyte 6.51 × 103/mm3 ± 2.864, platelet 168.62 × 103/mm3 ± 121.232, and uremic nitrogen 26.45 g/hari ± 32.268. The biggest plasma count 30%-70% with a percentage of 52.2%. The biggest proportion of the treatment is chemotherapy with a percentage of 100% and 73.9% of sample show improvement by the time they were discharged from hospital. Keywords: Multiple Myeloma, the characteristic of the patients, Sanglah