Antibacterial Activity of Ethanolic Extract of Red Frangipani Flowers (Plumeria rubra L.) on the Growth of the Bacteria Methicillin-resistant Staphylococcus aureus (MRSA)
| Main Authors: | Diksha, I Gusti Ngurah Ariestha Satya, Artini, I Gusti Ayu, Trapika, I Gusti Made Gde Surya Chandra, Widhiartini, Ida Ayu Alit |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Universitas Udayana
, 2024
|
| Online Access: |
https://ojs.unud.ac.id/index.php/eum/article/view/111892 https://ojs.unud.ac.id/index.php/eum/article/view/111892/55248 |
Daftar Isi:
- Introduction: MRSA is an antibacterial resistance problem that requires serious treatment. The limitations of antibacterials make it difficult to treat infections. The development of alternative antibacterial is needed. Objectives: This study shows the antibacterial effect of ethanol extract of Plumeria rubra L. flowers against MRSA bacteria. Methods: This research is a true experimental research with the only post-test control group design. The Kirby-Bauer test method was used to evaluate the antibacterial activity of ethanol extract of Plumeria rubra L. flowers with concentrations of 20%, 40%, and 60% in triplicate. The test bacteria used MRSA ATCC 33591 bacteria. Antibacterial activity was assessed from the diameter of the inhibition zone formed in bacterial cultures on agar media. Results: The inhibition zone were not formed after ethanolic extract of Plumeria rubra L. flowers at various concentrations. These were not antibacterial activity shown from Plumeria rubra L. flowers extract at concentrations of 20%, 40%, and 60%. Conclusions: The ethanolic extract of Plumeria rubra L. flowers does not show antibacterial activity against MRSA bacteria. Keywords: Red frangipani flowers (Plumeria rubra L.), antibacterial activity, MRSA.
- Pendahuluan: MRSA merupakan masalah resistensi antibakteri yang memerlukan penanganan serius. Keterbatasan antibakteri menyebabkan pengobatan infeksi menjadi sulit. Pengembangan antibakteri alternatif sangat diperlukan. Tujuan: Penelitian ini menunjukkan efek antibakteri ekstrak etanol bunga Plumeria rubra L. terhadap bakteri MRSA. Metode: Penelitian ini merupakan penelitian eksperimen murni dengan the only post-test control group design. Metode uji Kirby-Bauer digunakan untuk mengevaluasi aktivitas antibakteri ekstrak etanol bunga Plumeria rubra L. dengan konsentrasi 20%, 40%, dan 60% dalam rangkap tiga. Bakteri uji menggunakan bakteri MRSA ATCC 33591. Aktivitas antibakteri dinilai dari diameter zona hambat yang terbentuk pada kultur bakteri yang ditumbuhkan pada media agar. Hasil: Tidak terbentuk zona hambat pada pemberian ekstrak etanol bunga Plumeria rubra L. pada berbagai konsentrasi. Tidak terdapat aktivitas antibakteri ekstrak bunga Plumeria rubra L. pada konsentrasi 20%, 40%, dan 60%. Simpulan: Ekstrak etanol bunga Plumeria rubra L. tidak menunjukkan aktivitas antibakteri terhadap bakteri MRSA. Kata kunci: Bunga kamboja merah (Plumeria rubra L.), aktivitas antibakteri, MRSA.