EKSTRAK ETANOL UMBI UBI JALAR UNGU (Ipomoea batatas L) MENINGKATKAN KETEBALAN ENDOMETRIUM
| Main Authors: | Udiyani, Desak Putu Citra, Jawi, , I Made, Sugiritama, Wayan, Nyoman Arijana, I Gusti Kamasan, Sumadewi, Komang Trisna |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Universitas Udayana
, 2023
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| Online Access: |
https://ojs.unud.ac.id/index.php/eum/article/view/103732 https://ojs.unud.ac.id/index.php/eum/article/view/103732/51948 |
Daftar Isi:
- Menopause merupakan salah satu proses yang alami untuk Wanita, dengan terapi Hormone Replacement Therapy (HRT) menimbulkan efek endometriosis dan tromboemboli vena. Umbi ubi jalar ungu (Ipomoea batatas L) merupakan tumbuhan dengan antosianin yang mampu meningkatkan ploriferasi uterus. Tujuan penelitian: penelitian ini membuktikan ekstrak etanol umbi ubi jalar ungu (Ipomoea batatas L) mampu meningkatkan ketebalan endometrium uterus. Metoda penelitian: rancangan penelitian True Experimental-Post Test Only Control Group Design dimana 28 ekor tikus Wistar betina dikelompokkan menjadi 4 kelompok (@7 ekor tikus): P0 merupakan kelompok kontrol, P1 dengan esktrak dosis 10 mg/kgBB, P2 dengan dosis 30 mg/kgBB, dan P3 dosis 100 mg/kgBB diberikan selama 30 hari melalui sonde, pengangkatan uterus pada hari ke 30 dan mengamati ketebalan endometrium uterus. Hasil penelitian: ketebalan endometrium uterus antar kelompok perlakuan dengan rerata berbeda secara signifikan (p=0,000). Kelompok P3 dengan ketebalan endometrium paling tinggi. Kesimpulan: disimpulkan bahwa ekstrak etanol umbi ubi jalar ungu mampu meningkatkan ketebalan endometrium uterus tikus putih yang diovariektomi. Kata kunci: Ekstrak, ubi jalar ungu, antosianin, uterus
- Menopause is a natural process for women, with Therapy Hormone Replacement (HRT) causing the effects of endometriosis and venous thromboembolism. Purple sweet potato tuber (Ipomoea batatas L) is a plant with anthocyanins which can increase uterine proliferation. Purpose of the study: this study proved that the ethanol extract of purple sweet potato tubers (Ipomoea batatas L) can increase the thickness of the uterine endometrium. Research method: True Experimental-Post Test Only Control Group Design study in which 28 female Wistar rats were grouped into 4 groups (@7 rats): P0 was the control group, P1 with an extract dose of 10 mg/kg BW, P2 with a dose of 30 mg /kgBB, and P3 dose of 100 mg/kgBB given for 30 days through a sonde, removing the uterus on the 30th day and observing the thickness of the uterine endometrium. Results: uterine endometrial thickness between treatment groups with a significantly different average (p=0.000). P3 group with the highest endometrial thickness. Conclusion: it was concluded that the ethanol extract of purple sweet potato tubers was able to increase the uterine endometrial thickness of ovariectomized white rats. Keywords: Extract, Purple sweet potato, anthocyanin, uterus