Secondary Polycythemia in Hepatocellular Carcinoma: Treat or No Treat

Main Authors: Setiawan, Poernomo Budi, Maimunah, Ummi, Siagian, Nenci
Format: Article info application/pdf eJournal
Bahasa: eng
Terbitan: The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy , 2020
Subjects:
HCC
Online Access: http://www.ina-jghe.com/journal/index.php/jghe/article/view/740
http://www.ina-jghe.com/journal/index.php/jghe/article/view/740/622
Daftar Isi:
  • A 45-year man with a chronic hepatitis B virus (HBV) infection, elevated alphafetoprotein (AFP) 628ng/dL and Abdominal CT-scan features of Hepatocellular Carcinoma was admitted with polycythemia condition (haemoglobin 20.4g/dL, haematocrit 65.4%). Elevated of erythropoietin (EPO) serum level confirmed the polycythemia was because of HCC as a paraneoplastic syndrome. Based on diganosis criteria of HCC by PHPI 2017, the patient was diagnosed with HCC BCLC B and was treated with Trans arterial chemotherapy and embolization (TACE) with mixed doxorubicin. Aspirin 80mg once daily was given to patient to prevent thrombosis event. One month later after TACE, haemoglobin and haematocrite didn’t improve. Then 4 months later the patient died of cardiovascular event in the last admission at district hospital.