PREPARATION OF 2-AMINOETHYLSULFONIC ACID
| Main Authors: | Galuh Widiyarti, Muhammad Hanafi, L. Broto Sugeng Kardono, Ermawan ., Ngadiman ., Andini Sundowo |
|---|---|
| Format: | Article application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Directorate of Research and Community Engagement, Universitas Indonesia
, 2010
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| Online Access: |
http://journal.ui.ac.id/index.php/science/article/view/383 |
Daftar Isi:
- Preparation process of 2-aminoethylsulfonic acid (taurine) from ethanolamine, sulfuric acid and sodium sulfite has been studied. The process involves two steps of reactions, the first was esterification of ethanolamine (H2N-CH2-CH2-OH) with sulfuric acid to produce the intermediate product of 2-aminoethyl ester (H2N-CH2-CH2-OSO3H) which then was extended to the second step by sulfonation with sodium sulfite to produce 2-aminoethylsulfonic acid (H2N-CH2-CH2- SO3H). These two process conditions were observed by varying mole ratio of reactants, temperature and time period of reactions. Taurine product was qualitatively analyzed using 1H-NMR and LC-MS. Physical-chemical analysis were done by observing its melting point and determining its water, chloride and sulfate contents. Its melting point, water content, and sulfate content were 290oC, 0.303%, and 3 ppm, respectively, while its chloride content was undetected. After purification, the yield of process was 25.57%. Keywords: 2-aminoethylsulfonic acid, esterification, sulfonation, 1H-NMR, LC-MS