PERBANDINGAN BEBERAPA METODE DIAGNOSIS ANEMIA DEFISIENSI BESI: usaha mencari cara diagnosis yang tepat untuk penggunaan klinik
| Main Authors: | Suega, Ketu, Bakta, I Made, Adnyan, Losen, Darmayuda, Tjok |
|---|---|
| Format: | Article application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
journal of internal medicine
, 2012
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| Subjects: | |
| Online Access: |
http://ojs.unud.ac.id/index.php/jim/article/view/3803 |
Daftar Isi:
- Iron deficiency anemia (IDA) is the most widespread public health problems. In 1989 WHO report more than one third ofworlds population suffered from anemia and half of them with iron deficiency anemia. Iron deficiency anemia can cause reducedwork capacity in adults and impact motor and metal devolepment in children and adolescents. It also can increase risk of infection,mother mortality rate, affects cognition in adulescents girls and causes fatique in adult women. IDA may affect visual andauditory functioning and is weakly associated with poor cognitive development in children. The diagnosis of IDA requires properclinical manifestation, laboratory evidence and also others diagnostic test that support iron deficiency. There are some diagnostictests frequently use in clinical practice to diagnose IDA, such as the morphology of erytrosite, examination of serum iron andtotal iron binding capacity, examination of feritin serum, and bone marrow staining. Knowing the best of diagnostic methods canuse in clinical practice and also knowing the profile of IDA, can leads into better management of IDA in population. A diagnostictest was done in order to know the sensitivity and spesifity of erytrosite index, serum iron, TIBC, and feritin serum in dignosticIDA. The study was done at Internal Departement, Sanglah Hospital for 6 months, start from March 2003 until October 2003.The result is Feritin has the best sensitivity (90.6%) and specificity (90.6%) , with cut off point 35.4 μg/l. MCH as erytrosite indexhas sensitivity (84.4%) and specificity (75%) to diagnose IDA, the cut off point is 21.8 pg . Sensitivity and specificity of TIBC is81.3% and 83.8% with cutt off point 282 μg/l. Sensitivity and specificity saturation of transferin is 84.4% and 79.7% with cuttoff point 6%. Serum iron has sensitivity 75.0% and specificity 68.7% with cut off point 17 μg/l.