HUBUNGAN KONSUMSI SENG SEBAGAI KOFAKTOR MAKANAN TRADISIONAL MINANGKABAU DENGAN NEUTROFIL ELASTASE DALAM CAIRAN SULKUS GINGIVA PADA PENYAKIT PERIODONTAL (RELATION OF ZINC CONSUMPTION AS COFACTOR IN MINANGKABAU TRADITIONAL FOOD WITH NEUTROPHIL ELASTA
| Main Author: | Kasuma, Nila |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Fakultas Kedokteran Gigi USU
, 2017
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| Online Access: |
https://jurnal.usu.ac.id/index.php/dentika/article/view/14370 https://jurnal.usu.ac.id/index.php/dentika/article/view/14370/6297 https://jurnal.usu.ac.id/index.php/dentika/article/downloadSuppFile/14370/2802 |
Daftar Isi:
- Abstract This study involved 66 people consist of 22 healthy samples, mild gingivitis, and periodontitis samples. Enzyme levels were tested using ELISA technique. This is a cross-sectional study that compared the levels of enzyme neutrophil elastase in healthy samples, mild gingivitis and mild periodontitis in each group. Data was analyzed using univariate way to describe each variable, to see normal distribution (p> 0.05) Kolmogorov Smirnof Test was used. The levels of neutrophil elastase was the highest in mild periodontitis with an average of 9.42 ± 1.06 ng / dl. Levels of zinc consumption is the highest in healthy patients with an average of 6.39 ± 1.26 mg. Pearson Correlation Test was used to prove the relationship between the concentration of neutrophil elastase with zinc consumption in Minangkabau traditional food. The result showed that there was a significant relationship (p = 0,000) between neutrophil elastase concentration with zinc consumption levels in Minangkabau foods. The relationship between neutrophil elastase and zinc showed a strong correlation negative pathway (r = -0, 784). In conclusion, there was a relationship between neutrophil elastase with zinc as a cofactor in Minangkabau traditional food in periodontal disease. Key words: periodontitis, neutrophil elastase, zinc Abstrak Penelitian ini melibatkan 66 orang sampel terdiri atas 22 orang sehat, 22 orang mengalami gingivitis ringan dan 22 orang mengalami periodontitis awal. Kadar enzim yang diteliti diuji dengan menggunakan teknik ELISA. Rancangan penelitian adalah cross sectional yang membandingkan kadar enzim netrofil elastase pada sampel sehat, gingivitis ringan dan periodontitis awal. Untuk melihat distribusi normal (p> 0,05) dilakukan tes Kolmogorov Smirnof. Terdapat kadar neutrofil elastase yang paling tinggi pada periodontitis ringan dengan rata-rata 9,42 ± 1,06 ng/dl. Kadar konsumsi seng yang paling tinggi adalah pada pasien sehat dengan rata-rata 6,39 ± 1,26 mg. Tes Pearson correlation digunakan untuk membuktikan hubungan antara konsentrasi neutrofil elastase dengan konsumsi seng pada makanan tradisional Minangkabau. Hasil penelitian menunjukkan korelasi yang signifikan ( p= 0,000) antara konsentrasi neutrofil elastase dengan kadar konsumsi seng pada makanan tradisional Minangkabau. Hubungan antara neutrofil elastase dan seng menunjukkan korelasi yang kuat berarah negatif (r= -0,784). Sebagai kesimpulan, terdapat hubungan konsumsi seng sebagai kofaktor makanan tradisional Minangkabau dengan neutrofil elastase dalam gingival crevicular fluid penyakit periodontal. Kata kunci: periodontitis, neutrofil elastase, seng