FORMULASI GRANUL INSTAN EKSTRAK KELOPAK BUNGA ROSELLA MERAH (Hibiscus sabdariffa L.) SEBAGAI MINUMAN ANTIOKSIDAN
| Main Authors: | Saptarini, Nyi Mekar; Fakultas Farmasi, Universitas Padjadjaran Jl. Raya Bandung Sumedang KM 21, Jatinangor 45363, Darusman, Fitrianti; Jurusan Farmasi, FMIPA, Universitas Islam Bandung Jl. Tamansari no.1 Bandung 40116, Kuntari, Diah Sri; Jurusan Farmasi, FMIPA, Universitas Al Ghifari Jl. Cisaranten Kulon No. 140 Soekarno-Hatta Bandung 40293. |
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| Format: | Article application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Badan Penelitian dan Pengembangan Kesehatan
, 2012
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| Subjects: | |
| Online Access: |
http://ejournal.litbang.depkes.go.id/index.php/toi/article/view/8865 |
Daftar Isi:
- ABSTRACTRed roselle (Hibiscus sabdariffa L.) calyx contains vitamin C and flavonoids that had potential as antioxidants.The aim of this study was to create an instant granules formula preparation of red roselle calyx extract. The stepsin this study consisted of plant determination, phytochemical screening, maceration with 70% ethanol, formulationof instant granules with wet granulation method, instant granules evaluation, testing the instant granules stability, and the hedonic test. Phytochemical screening showed the red roselle calyx contain saponins, flavonoids,quinones, steroids, and vitamin C. The maceration rendement was 28.57%. The characteristic of instant granuleswas moisture content 1.42-1.83%, flow rate 7.519-9.054 g/s, angle of repose 21.893-28.309o, true density 0.752-0.823 g/ml, tapped density 0.883-0.968 g/ml, and the dissolving speed 0.083-0.101 g/s. The best and the mostfavourable instant granules was formula III.ABSTRAKKelopak bunga rosella merah (Hibiscus sabdariffa L.) mengandung vitamin C dan flavonoid yang berkhasiat sebagaiantioksidan. Penelitian ini bertujuan untuk membuat formula sediaan granul instan dari ekstrak kelopakbunga rosella merah. Tahapan penelitian meliputi determinasi tanaman, penapisan fitokimia, maserasi denganetanol 70%, formulasi granul instan dengan metode granulasi basah, evaluasi granul instan, uji stabilitasgranul instan, dan uji kesukaan. Penapisan fitokimia menunjukkan kelopak bunga rosella merah mengandungsaponin, flavonoid, kuinon, steroid, dan vitamin C. Maserasi menghasilkan rendemen sebesar 28,57%. Hasilpenelitian menunjukkan granul instan memiliki kadar air 1,42-1,83%, kecepatan alir 7,519-9,054 g/detik,sudut istirahat 21,893-28,309o, kerapatan nyata 0,752-0,823 g/ml, kerapatan mampat 0,883-0,968 g/ml, dankecepatan melarut 0,083-0,101 g/detik. Formula III merupakan formula granul instan yang paling baik danpaling disukai.