Genotype and transmission Human Immunodeficiency Virus-1 in seven provinces in Indonesia
| Main Authors: | Roselinda, Roselinda; Center for Biomedical and Basic Technology of Health, National Institute of Health Research and Development, Ministry of Health of Indonesia, Jekti, Rabea Pangerti; Center for Biomedical and Basic Technology of Health, National Institute of Health Research and Development, Ministry of Health of Indonesia |
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| Format: | Article application/pdf eJournal |
| Bahasa: | ind |
| Terbitan: |
Badan Penelitian dan Pengembangan Kesehatan
, 2013
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| Subjects: | |
| Online Access: |
http://ejournal.litbang.depkes.go.id/index.php/HSJI/article/view/3070 |
Daftar Isi:
- AbstrakLatar belakang: Penelitian sebelumnya di Indonesia dengan sampel terbatas mengungkapkan bahwa distribusi subtipe HIV-1 dan modus penularan berbeda antar daerah. Tujuan analisis ialah untuk mengungkapkan subtipe dan cara penularan HIV-1 di daerah yang lebih luas di Indonesia.Metode: Tulisan ini menggunakan sebagian data studi potong lintang di tujuh provinsi di Indonesia pada 2011 di antara kasus HIV/AIDS yang dipilih purposif yang mengunjungi klinik Perawatan Sukarela dan Pengobatan (VCT) di tujuh provinsi (Sumatera Utara, Sumatera Barat, Kepulauan Riau, Sulawesi Selatan, Sulawesi Utara, Maluku, dan Papua). Untuk setiap provinsi yang dipilih 1 atau 2 rumah sakit secara purposif.Hasil: Subtipe AE terdapat di semua propinsi sampel. Subtipe B ditemukan di hampir semua provinsi kecuali di Kepulauan Riau. Jenis lainnya (A, C, dan AG) ditemukan hanya di 2 provinsi, dan jenis yang paling langka (D) ditemukan hanya di satu provinsi. Proporsi penularan yang tinggi yaitu melalui heteroseksual di semua provinsi kecuali di Sulawesi Selatan. Persentase tertinggi transmisi via suntikan vena (IDU) terdapat di Sulawesi Selatan, dan melalui transmisi perinatal terjadi di Papua.Kesimpulan: Distribusi Subtipe dan cara penularan HIV-1 berbeda antar propinsi. Subtipe AE terdapat di seluruh provinsi, sedangkan proporsi tertinggi transmisi melalui perinatal terjadi di Papua. (Health Science Indones 2012;2:xx-xx)Kata kunci:HIV-1 subtipe, distribusi, cara penularan, IndonesiaAbstractBackground:Previous studies in Indonesia with a limited sample of HIV-1 subtypes revealed that HIV-1 subtype distribution and mode of transmission differed between the regions. This analysis aimed to describe subtypes and mode of transmission of HIV-1 in wider area in Indonesia.Methods:This analysis used a part of HIV/AIDS cross sectional study in seven provinces in Indonesia in 2011 among HIV/AIDS purposive selected cases visited Volunteer Care and Treatment (VCT) clinics in seven provinces (North Sumatera, West Sumatera, Riau islands, South Sulawesi, North Sulawesi, Maluku, and Papua). For each province was selected 1 or 2 hospitals purposive.Results: AE subtype of HIV-1 was existed in all participating. Subtype B was found in almost all provinces except in Riau islands. The other type (A, C, and AG) found in 2 provinces only, and the rarest type (D) found in one province only.The high proportion of transmission was through heterosexual in all provinces except in South Sulawesi. The percentage of the common transmission by intra venous drug user (IDU) IDU occurred in South Sulawesi, whereas via perinatal transmission occurred in Papua.Conclusion: HIV-1 subtype distribution and mode of transmission differed between the provinces. The AE subtype HIV-1 was existed in all provinces, whereas among provinces the highest proportion transmission via perinatal occurred in Papua. (Health Science Indones 2012;2:xx-xx)Key words: HIV-1 subtype, distribution, mode of transmission, Indonesia