Pengaruh ekstrak etanol temulawak terhadap viabilitas streptococcus mutans dan aggregatibacter actinomycetemcomitans (kajian dental biofilm studi in vitro) = The effect of curcuma xanthorrhiza ethanol extract to the viability of streptococcus mutans and aggregatibacter actinomycetemcomitans dental biofilm research in vitro study
| Main Author: | Royan Diana, author |
|---|---|
| Format: | Bachelors |
| Terbitan: |
[;Universitas Indonesia. Fakultas Kedokteran Gigi, Fakultas Kedokteran Gigi Universitas Indonesia]
, 2015
|
| Subjects: | |
| Online Access: |
http://lib.ui.ac.id/file?file=digital/2016-6/20421409-S-Royan Diana.pdf |
Daftar Isi:
- Temulawak memiliki efek antibakteri. S. mutans dan A. actinomycetemcomitans merupakan bakteri penyebab karies dan penyakit periodontal. Tujuan: Membandingkan efek ekstrak etanol temulawak terhadap viabilitas biofilm S. mutans dan A actinomycetemcomitans single dan dual species dalam berbagai fase pembentukan. Metode: Model biofilm diinkubasi selama 4 jam, 12 jam, dan 24 jam, kemudian dipapar ekstrak etanol temulawak 0,5%-25%. Hasil: Viabilitas biofilm single species S. mutans lebih rendah (p<0,05) dibanding kelompok biofilm lain. Tidak ada perbedaan bermakna (p>0,05) antara viabilitas biofilm single species A. actinomycetemcomitans dan biofilm dual species. Kesimpulan: Ekstrak etanol temulawak lebih efektif menurunkan viabilitas biofilm single species S. mutans <hr> Curcuma xanthorrhiza has antibacterial property. S. mutans and A. actinomycetemcomitans cause caries and periodontal disease. Aim: Comparing Curcuma xanthrorrhiza ethanol extract’s to the viability of S. mutans and single and dual-species A. actinomycetemcomitans biofilm in different formation phases. Methods: Biofilm models were incubated for 4, 12, and 24 hours, then exposed to 0.5%-25% Curcuma xanthorrhiza extract. Result: Single species S. mutans biofilm’s viability was significantly lower than other biofilm groups (p<0.05). Viability of single-species and dual-species A. actinomycetemcomitans biofilm showed no significant difference (p>0.05). Conclusion: Curcuma xanthorrhiza ethanol extract is more effective in decreasing the single-species S. mutans biofilm’s viability