BACE lead target for orchestrated therapy of alzheimer’s disease / edited by Varghese John
Format: | Book Bachelors |
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Terbitan: |
John Wiley & Sons
, 2010
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Subjects: | |
Online Access: |
http://lib.ui.ac.id/file?file=digital/2015-12/20410879-01-fmatter.pdf |
Daftar Isi:
- BACE (β-site of APP cleaving enzyme) is a critical component in Alzheimer's Disease (AD), and the development of BACE inhibitors shows great potential as a therapy for the disease. BACE : lead target for orchestrated therapy of alzheimer's disease covers virtually all aspects of BACE from initial identification, discovery of inhibitors, and challenges in clinical development, while providing a global understanding essential for productive and successful drug discovery.