BACE lead target for orchestrated therapy of alzheimer’s disease / edited by Varghese John

Format: Book Bachelors
Terbitan: John Wiley & Sons , 2010
Subjects:
Online Access: http://lib.ui.ac.id/file?file=digital/2015-12/20410879-01-fmatter.pdf
Daftar Isi:
  • BACE (β-site of APP cleaving enzyme) is a critical component in Alzheimer's Disease (AD), and the development of BACE inhibitors shows great potential as a therapy for the disease. BACE : lead target for orchestrated therapy of alzheimer's disease covers virtually all aspects of BACE from initial identification, discovery of inhibitors, and challenges in clinical development, while providing a global understanding essential for productive and successful drug discovery.