Efek bubuk susu kedelai terbadap kadar kolesterol LDL dan HDL serum wanita perimenopause dengan hiparkolesterolernia = The effects of soy milk powder on LDL and HDL serum cholesterol levels in hypercholesterolemic perimenopausal women
| Main Authors: | Retno Kuntari Heruyanto, author, Add author: Sri Sukmaniah, supervisor, Add author: Sri Widia Jusman, supervisor, Add author: Saptawati Bardosono, examiner, Add author: Ani Retno Prijanti, examiner, Add author: Fikri Effendy, examiner, Add author: Dante Saksono Harbuwono, examiner |
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| Format: | Masters Bachelors |
| Terbitan: |
, 2009
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| Subjects: | |
| Online Access: |
https://lib.ui.ac.id/detail?id=20341297 |
Daftar Isi:
- <b>ABSTRAK</b><br> Tujuan penelitian ini adalah untuk mengetahui efek pamberian bubuk susu kedelai 2x30 gramlbari, selama 8 minggu terhadap kadar kolesterol LDL dan HDL serum pada wanita parimenopause Bertempat di Klinik Seruni Departemen Ilmu Gizi Fakultas Kedokteran Universitas lndnesia, jalan Salemba Raya no.6, Jakarta Penelitian dengan rancangan one group pre-post tes yang telah disetujui Komite Etik FKUI. Subyek mendapat suplementasi susu bubuk kedelai 2x30 g/hari selama 8 minggu. Pada awal (minggu 0); pertengahan (minggu IV); dan akhir penelitian ( awal minggu IX) dilakukan pemeriksaan kadar kolesterol LDL dan HDL. Data isilpan zat gizi dilukukan sebelum dan selama penelitian berlangsung, dengan menggnnakan food recall l x24 jam. Uji statistik yang digunakan adalah uji t berpasangan jika data berdistnbusi normal dan Wilcoxon, jika data berdistribusi tidak normal. Tingkat kemaknaan yang digunakan p<0,05. Sebanyak 19 subyek penelitian yang dapat mengikuti penelitian sampai selesai. Setelah delapan minggu perlakuan, didapatkan adanya penurunan yang bermakna (p<0,05) pada kadar kole-ol LDL, yaitu sebesar 8,59±17,31% di minggu IV dan 7,81±11,32% di minggu IX. Kadar kolesterol HDL menurun pada minggu IV dan IX, namun tidak bermakna (p>0,05). Rasio kolesterol LDL terhadap HDL, men= secilla bermakna (p<0,05) di minggu IV, yaitu sebesar 7,03±16,82%, sedangkan di minggu IX terjadi penurunan, namun tidak bermakna (p>0,05), sebesar 4,04±12,25%. Pemberian bubuk susu kedelai 2x30 g/hari selama delapan minggu, dapat menurunkan kadar kolesterol LDL serta rasio LDLIHDL secara bermakna. <hr> <b>Abstract</b><br> This research aim to investigate the effects of2x30 lifd soy milk flour, for eight . weeks on serumo cholesterol LDL andHDL levels in hypercholesterolemic perimenopausal women Located at Seruni Clinic, Depar1ment of Nutrition, Faculty of Medicine University of Indonesia The study was a one group pre-post test design, which was approved by The Ethical Clearance Research Committee of Faculty of Medicine University of Indonesia. The subjects received 2x30 g/d soy milk powder for eight weeks. Serum LDL and HDL cholesterol levels were determined at the heghming (week 0), the middle (week4), and the end of the stndy(early week 9). Dietery intakes were assessed using lx24 hours food recall. Statistical analysis was performed using dependent t tes for normal distribution and Wilcoxon for not normal distribution data. The level of significancy was 5% (p<0,05) There were 19 subjects who completed the study. After eight weeks intervention, there was 8.59±17.31% significant decreased in LDL cholesterol levels at the 4th week of the study and 7.81±1 1.32% at the s"' week of the study (p<0,05).HDL cholesterol levels decreased at the 4\h and 8" weeks, but not significant(p>0,05). The ratio ofLDL to HDL was 7,03±16,82o/o, which was significant decreased at the 4" week (p<0,05), while at the 9th week the decrement was not significant (4.04±12.25%), p> 0.05. Consuming soy milk powder 2 x 30 g/dduring eight weeks, can reduce the LDL cholesterol level and LDLIIIDL ratio significantly.