Pengaruh pemberian tempe terhadap kadar Glukosa Darah penderita diabetes melitus tipe 2 usia laujut = the effect of tempe administration on plasma glucose level in elderly patients with type 2 diabet mellitus
| Main Authors: | Grace Puspasari, author, Add author: Drupadi H.S. Dillon, supervisor, Add author: Budiman, supervisor, Add author: Dante Saksono Harbuwono , examiner, Add author: Parwati Abadi, examiner, Add author: Luciana B. Sutanto, examiner, Add author: Dewi Friska, examiner |
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| Format: | Masters Bachelors |
| Terbitan: |
, 2010
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| Subjects: | |
| Online Access: |
https://lib.ui.ac.id/detail?id=20339940 |
Daftar Isi:
- [<b>ABSTRAK</b><br> Tujuan penelitian adalah diketahuinya pengaruh pemberian 100 gram tempe per hari selama empat minggu terbadap kadar glukosa darah peda penderita diabetes melitus (DM) tipe 2 usia lanjut (usila). Penelitian ini merupakan uji klinis parael acak, terbuka. Subyek penelitian adalah 30 orang penderita. DM tipe 2 usila yang tinggal di empat panti wredha di Jakarta. Alokasi acak dengan cara randomisasi blok dilakukan untuk membagi subyek menjadi dua kelompok. Seluruh subyek diberikan pengaturan diet DM sesuai PERKENI. Kelompok P sebanyak 16 orang yang diberikan 100 gram tempe, sedangkan kelompok K sebanyak 14 orang yang diberikan kacang-kacangan pengganti tempe. Data yang diambil mcliputi usia, jenis kelamin. berat badan dan indeks massa tubub (IMT), serta data asupan dengan metode food record, Pemeriksaan kadar glukosa darah puasa (GDP) dan glukosa darah 2 jam postprandial (GDPP) dilukukan pada awal dan akhir perlakuan. Analisis data menggunakan uji t tidak berpasangan dan uji Mann Whitney dengan batas kemaknaan 5%. Subyek yang mengikuti penelitian secara lengkap sebanyak 27 orang yang terdiri dari I5 orang kelompok perlakuan dan 12 orang kelompok kontrol. Rerata usia. subyek adalah 70,4±9,5 tabun. Mayoritas subyek (63,5%) adalah perempuan. dan hampir setengah jumlah subyek mempunyai status gill normal berdasarkan IMT. Sebegian besar (80%) subyek belum menerima obet DM. Pada awal penelitian. usia, jenis kelamin, IMT asupan kalori dan zat gizi subyek tidak menunjukkan perbedaan bermakna (p>(0,05). Seluruh subyek tidak dapat mematuhi anjuran diet DM yang diberikan asupan lemak: subyek tinggi sedangkan asupan serat rendah. Setelah perlakuan terlihat kecenderungan penurunan kadar GDP dan peningkatan kadar GDPP yang tidak berbeda bermakna antara kelompok P dan K. Pemberian 1 00 gram tempe selama empat minggu tidak menurunkan kadar GDP dan GDPP. <hr> <b>ABSTRACT</b><br> The aim of this study was to investigate the effect of daily intake of I 00 gram tempe for four weeks on plasma glucose level in elderly patients with type 2 diabetes mellitus. This study was a parallel randomized clinical trial Subjects were 30 diabetic elderly living in four nursing homes in Jakarta. In the study. subjects were assigned into hvo groups using block randomization. All subjects had to take diabetic regiment with calorie and macrooutrient following diabetic recommendation diet The treatment group (n=l6) received tempe, while control group (n=l4} received legumes other than tempe. Data collection included age, sex, body weight, body mass index. and nutrient intake using 3x24 hours food records. In addition isoftavone intake was also assessed. Fasting plasma glucose levels (FPG) and 2 hours postprandial plasma glucose (PPPG) levels were assessed befure and afier int<rventio!L Unpaired !-test and Mann Whltuey were used to analysed data with the 5% significance level. There were 27 subjects completed the study: 15 of treatment group and 12 of control group. Mean of age were 70.4 ± 9.5 years.Majority (63.5%) of subjects were female, and ahnost balf subjects had normal BML About 800/o of subjects did not use diabetic medication. At base line age, BMI, sex. use of diabetic medication. calorie and macronutrient intake were comparable. All subjects could not comply with diabetic regiment: bigh fat and low fiber intakes. Fat, fiber nod isoflarone inU!ke were signifieantiy higher in treatment group compare to control group. Decrease in FPG and increase in PPPG after intervention were observed but were statisticaJy insignificant. In conclusion, daily intake of 100 gram tempe for four weeks did . not deereose FPG and PPPG. ;The aim of this study was to investigate the effect of daily intake of I 00 gram tempe for four weeks on plasma glucose level in elderly patients with type 2 diabetes mellitus. This study was a parallel randomized clinical trial Subjects were 30 diabetic elderly living in four nursing homes in Jakarta. In the study. subjects were assigned into hvo groups using block randomization. All subjects had to take diabetic regiment with calorie and macrooutrient following diabetic recommendation diet The treatment group (n=l6) received tempe, while control group (n=l4} received legumes other than tempe. Data collection included age, sex, body weight, body mass index. and nutrient intake using 3x24 hours food records. In addition isoftavone intake was also assessed. Fasting plasma glucose levels (FPG) and 2 hours postprandial plasma glucose (PPPG) levels were assessed befure and afier int<rventio!L Unpaired !-test and Mann Whltuey were used to analysed data with the 5% significance level. There were 27 subjects completed the study: 15 of treatment group and 12 of control group. Mean of age were 70.4 ± 9.5 years.Majority (63.5%) of subjects were female, and ahnost balf subjects had normal BML About 800/o of subjects did not use diabetic medication. At base line age, BMI, sex. use of diabetic medication. calorie and macronutrient intake were comparable. All subjects could not comply with diabetic regiment: bigh fat and low fiber intakes. Fat, fiber nod isoflarone inU!ke were signifieantiy higher in treatment group compare to control group. Decrease in FPG and increase in PPPG after intervention were observed but were statisticaJy insignificant. In conclusion, daily intake of 100 gram tempe for four weeks did . not deereose FPG and PPPG. , The aim of this study was to investigate the effect of daily intake of I 00 gram tempe for four weeks on plasma glucose level in elderly patients with type 2 diabetes mellitus. This study was a parallel randomized clinical trial Subjects were 30 diabetic elderly living in four nursing homes in Jakarta. In the study. subjects were assigned into hvo groups using block randomization. All subjects had to take diabetic regiment with calorie and macrooutrient following diabetic recommendation diet The treatment group (n=l6) received tempe, while control group (n=l4} received legumes other than tempe. Data collection included age, sex, body weight, body mass index. and nutrient intake using 3x24 hours food records. In addition isoftavone intake was also assessed. Fasting plasma glucose levels (FPG) and 2 hours postprandial plasma glucose (PPPG) levels were assessed befure and afier int<rventio!L Unpaired !-test and Mann Whltuey were used to analysed data with the 5% significance level. There were 27 subjects completed the study: 15 of treatment group and 12 of control group. Mean of age were 70.4 ± 9.5 years.Majority (63.5%) of subjects were female, and ahnost balf subjects had normal BML About 800/o of subjects did not use diabetic medication. At base line age, BMI, sex. use of diabetic medication. calorie and macronutrient intake were comparable. All subjects could not comply with diabetic regiment: bigh fat and low fiber intakes. Fat, fiber nod isoflarone inU!ke were signifieantiy higher in treatment group compare to control group. Decrease in FPG and increase in PPPG after intervention were observed but were statisticaJy insignificant. In conclusion, daily intake of 100 gram tempe for four weeks did . not deereose FPG and PPPG. ]