Studi Kimia dan Farmakologi: Tumbuhan Obat Indonesia, Kayu Lawang, ( Cinnamomum culilaban (L.) Presl.)
| Main Authors: | Yatri Hapsari, author, Add author: Antonius Herry Cahyana, supervisor, Add author: Simanjuntak, Partomuan, supervisor, Add author: Soleh Kosela, examiner, Add author: Emil Budianto, examiner, Add author: , Add author: Endang Saefudin, examiner |
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| Format: | Masters Bachelors |
| Terbitan: |
, 2010
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| Subjects: | |
| Online Access: |
https://lib.ui.ac.id/detail?id=20279432 |
Daftar Isi:
- [<b>ABSTRAK</b><br> Penelitian ini bertujuan untuk mengetahui aktivitas farmakologis dan senyawa kimia yang terkandung pada tanaman obat Indonesia, kayu lawang (Cinnamomum culilaban (L.) Presl.). Kayu lawang selama ini dimanfaatkan oleh masyarakat setempat sebagai obat tradisional dan masih sedikit penelitian ilmiah yang mempelajari tanaman ini. Oleh karena itu, pada penelitian ini dilakukan maserasi bertahap dengan n-heksan, etil asetat, metanol dan air. Keempat ekstrak dilakukan penapisan fitokimia, uji antimkroba, uji antioksidan dan uji toksisitas. Ekstrak etil asetat yang paling tinggi aktivitas toksisitas dan antioksidannya, difraksinasi dengan kromatografi kolom lalu fraksi-fraksi hasil kromatografi kolom diuji aktivitas antioksidannya. Didapat dua fraksi yang aktivitas antioksidannya tinggi dan diidentifikasi senyawa kimianya dengan KG-SM dan RMI adalah eugenol dan 4-hidroksi-2-metoksi sinamaldehid. <hr> <b>ABSTRACT</b><br> The aim of this study is to study pharmacological activities and chemical compounds of Indonesian medicinal plants, kayu lawang (Cinnamomum culilaban (L.) Presl.). Kayu lawang has been used by local people as traditional medicine and only a few scientific research studied this plant. In this study kayu lawang was extracted using n-hexane, ethyl acetate, methanol and water as solvents. All exctracts were subjected to phytochemical screening, antimicrobial, antioxidant and toxicity assays. Ethyl acetate extract that showed the highest activity compared to the other extracts, were then fractionated using column chromatography and antioxidant assay was conducted on fractions of these extracts. Two fractions were found to have high antioxidant activity and were identified as being eugenol and 4-hidroxy-2-methoxy cinnamaldehyde using GC-MS and NMR;The aim of this study is to study pharmacological activities and chemical compounds of Indonesian medicinal plants, kayu lawang (Cinnamomum culilaban (L.) Presl.). Kayu lawang has been used by local people as traditional medicine and only a few scientific research studied this plant. In this study kayu lawang was extracted using n-hexane, ethyl acetate, methanol and water as solvents. All exctracts were subjected to phytochemical screening, antimicrobial, antioxidant and toxicity assays. Ethyl acetate extract that showed the highest activity compared to the other extracts, were then fractionated using column chromatography and antioxidant assay was conducted on fractions of these extracts. Two fractions were found to have high antioxidant activity and were identified as being eugenol and 4-hidroxy-2-methoxy cinnamaldehyde using GC-MS and NMR;The aim of this study is to study pharmacological activities and chemical compounds of Indonesian medicinal plants, kayu lawang (Cinnamomum culilaban (L.) Presl.). Kayu lawang has been used by local people as traditional medicine and only a few scientific research studied this plant. In this study kayu lawang was extracted using n-hexane, ethyl acetate, methanol and water as solvents. All exctracts were subjected to phytochemical screening, antimicrobial, antioxidant and toxicity assays. Ethyl acetate extract that showed the highest activity compared to the other extracts, were then fractionated using column chromatography and antioxidant assay was conducted on fractions of these extracts. Two fractions were found to have high antioxidant activity and were identified as being eugenol and 4-hidroxy-2-methoxy cinnamaldehyde using GC-MS and NMR, The aim of this study is to study pharmacological activities and chemical compounds of Indonesian medicinal plants, kayu lawang (Cinnamomum culilaban (L.) Presl.). Kayu lawang has been used by local people as traditional medicine and only a few scientific research studied this plant. In this study kayu lawang was extracted using n-hexane, ethyl acetate, methanol and water as solvents. All exctracts were subjected to phytochemical screening, antimicrobial, antioxidant and toxicity assays. Ethyl acetate extract that showed the highest activity compared to the other extracts, were then fractionated using column chromatography and antioxidant assay was conducted on fractions of these extracts. Two fractions were found to have high antioxidant activity and were identified as being eugenol and 4-hidroxy-2-methoxy cinnamaldehyde using GC-MS and NMR]