Human Pleckstrin Homology domain Interacting Protein (PHIP); A Target Enabling Package
| Main Authors: | Oakley B. Cox, Tobias Krojer, Patrick Collins, Octovia Monteiro, Romain Talon, Anthony Bradley, Oleg Fedorov, Jahangir Amin, Brian D. Marsden, John Spencer, Frank von Delft, Paul Brennan |
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| Format: | info dataset eJournal |
| Terbitan: |
, 2016
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/4134700 |
Daftar Isi:
- SGC Oxford has expressed, purified and crystallized the second bromodomain of PHIP as part of the probe programme. Fragment screening and X-ray crystallography identified binders, some of which optimised to uM affinity. However, molecules with probe properties were not obtained. Consequently it has been decided to put the information generated into the public domain.
- This document represents version 6 of the TEP datasheet and includes all updates on the project as of October 2020. For more information about TEPs and the TEP Programme, please visit https://thesgc.org/tep.