New Perspective in Obstructive Sleep Apnea Syndrome – The Use of Biomarkers as a Screening Tool
| Main Authors: | Diana-Cristina Protasiewicz-Timofticiuc, Maria Moța |
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| Format: | Article eJournal |
| Terbitan: |
, 2020
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/4121777 |
Daftar Isi:
- The sedentary lifestyle and extreme environmental changes led to a 3-fold increase in obesity prevalence since 1975. Although obesity can be prevented, once appeared it represents a major risk factor in developing/progression of obstructive sleep apnea syndrome (OSAS) and other comorbidities. Nowadays, the prevalence of OSAS is also continuously growing in an exponential mode, making it obvious that a new approach is needed. The association between obesity and OSAS has been described since ancient time and only recently has become of great interest worldwide because of its great impact on people’s quality of life. Obesity and OSAS represent a major health problem because of the increased risk of cardiovascular diseases (CVD), systemic inflammation, metabolic disorders, dyslipidemia, non-alcoholic fatty liver disease (NAFLD), hyperuricemia, gout, chronic kidney disease (CKD), depression, anxiety, cognitive impairment, neurological disorders, excessive daytime sleepiness, decreased vigilance leading to road traffic accidents. The polysomnography is considered to be the “gold standard method” to diagnose OSAS and its severity, but finding a new and non-invasive screening tool is becoming vital because of the worldwide disease impact upon the quality of life and also by judging the need of achieving a long-lasting therapeutic control.