EVALUATION OF SAFETY AND EFFICACY OF INTRAVENOUS IRON SUCROSE IN PATIENTS WITH IRON DEFICIENCY ANEMIA
| Main Authors: | Dr. Jay B. Patel, Gaurav Rajauria, Dr. Yogesh Kumar Kansara, Dr. Kanchi Desai |
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| Format: | Article eJournal |
| Terbitan: |
, 2020
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/3906788 |
Daftar Isi:
- Background: Iron deficiency is the most common disorder in the world, affecting approximately 25% of the world`s population and the most common cause of anemia. Objective: to evaluate the safety and efficacy of intravenous iron sucrose in patients with iron deficiency anemia. Methods: Thirty two adult patients with hemoglobin<8.0 g/dl and <7.63\lng/mlserum ferritin were included. who had intolerance or showed no effect with oral iron therapy, received a weekly dose of 200 mg of intravenous iron sucrose until the hemoglobin level was corrected or until receiving the total dose of intravenous iron calculated for each patient. Results: The mean hemoglobin and serum ferritin levels were <8.0 g/dl and 7.63ng/ml\l (pretreatment) and 13.1 g/dl and 96.20 ng/ml\l (post-treatment) (p-value < 0.0001), respectively. The average increases in hemoglobin levels were 4.29 g/dL for women and 5.58 g/dl for men; 96% of male and 87% of female patient’s responded hemoglobin increased by intravenous iron therapy. Conclusion: It was concluded that the use of intravenous iron sucrose is a safe and effective in the treatment of adult patients with iron deficiency anemia who lack satisfactory response to oral iron therapy.