MICROSPHERE: A NOVEL DRUG DELIVERY SYSTEM

Main Author: R. R. Thenge, M. P. Chandak, V. S. Adhao
Format: Article eJournal
Terbitan: , 2020
Subjects:
Online Access: https://zenodo.org/record/3783638
Daftar Isi:
  • Abstract: Microspheres are normally free flowing powders contains proteins or synthetic polymers which has biodegradable in nature and having a particle size but 200-500 μm. Number of techniques for the preparation of microspheres offers a spread of opportunities to regulate aspects of drug administration and enhance the therapeutic efficacy of a drug. A neat controlled drug delivery system can overcome a number of problems of conventional therapy and enhance therapeutic efficacy of the drug. There are various approaches in delivering therapeutic substance to the target site in sustained and controlled release fashion. These are prepared by methods like Single emulsion, Double emulsion, Polymerization, Phase separation coacervation, Emulsion solvent evaporation and solvent diffusion. Microspheres are having wide selection of applications due to controlled and sustained release.