The Molecular Diversity Scope of Urazole in the Synthesis of Organic Compounds
| Main Authors: | Ghodsi M. Ziarani, Fatemeh Mohajer, , Razieh Moradi, Parisa Mofatehnia. |
|---|---|
| Format: | Article eJournal |
| Terbitan: |
, 2019
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| Online Access: |
https://zenodo.org/record/3594113 |
Daftar Isi:
- As a matter of fact, nitrogen as a hetero atom among other atoms has had an important role in active biological compounds. Since heterocyclic molecules with nitrogen are highly demanded due to biological properties, 4-phenylurazole as a compound containing nitrogen might be important in the multicomponent reaction used in agrochemicals, and pharmaceuticals. Considering the case of fused derivatives “pyrazolourazoles” which are highly applicable because of their application for analgesic, antibacterial, anti-inflammatory and antidiabetic activities as HSP-72 induction inhibitors (I and III) and novel microtubule assembly inhibitors. It should be mentioned that spiro-pyrazole also has biological activities like cytotoxic, antimicrobial, anticonvulsant, antifungal, anticancer, anti-inflammatory, and cardiotonic activities.