Thermal monitoring during photothermia: hybrid probes for simultaneous plasmonic heating and near-infrared optical nanothermometry
| Main Authors: | Quintanilla, M, Garcia, I, de Lazaro, I, Garcia-Alvarez, R, Henriksen-Lacey, M, Vranic, S, Kostarelos, K, Liz-Marzan, LM |
|---|---|
| Format: | Article eJournal |
| Terbitan: |
, 2019
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| Online Access: |
https://zenodo.org/record/3532970 |
Daftar Isi:
- The control of temperature during photothermal therapy is key to preventing unwanted damage in surrounding tissue or post-treatment inflammatory responses. Lack of accurate thermal control is indeed one of the main limitations that hyperthermia techniques present to allow their translation into therapeutic applications. We developed a nanoprobe that allows controlled local heating, combined with in situ nanothermometry. The design of the probe follows a practical rationale that aims at simplifying experimental requirements and exploits exclusively optical wavelengths matching the first and second biological windows in the near-infrared.