The Role of Arena Virus Protein and Their Molar Ratio
| Main Authors: | Abdullah Sethar D.V.M., M. Sc, Dr. Benjamin W. Neuman, M.Ali Bhatti,, Dr. Gul Hassan Sethar, Dr. Nargis Khan, Hassan Sethar |
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| Format: | Article eJournal |
| Bahasa: | eng |
| Terbitan: |
, 2016
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/3531390 |
Daftar Isi:
- The current investigates the role of Arenavirus protein and their molar ratio. The arenavirus L protein has the characteristic sequence motifs conserved among the RdRp (L proteins) of NS RNA virus. The proposed polymerase module of L is located within domain 3 which contains highly conserved amino acids within motifs designated A and C. The L RNA segment encodes a high-molecular-mass protein (L; ca. 200 kDa) which has the characteristic motifs conserved in all the viral RNA dependent RNA polymerases and a small polypeptide Z (ca.11 kDa) which contains a RING finger motif and whose function is unknown (1, 19, 33) . The L RNA segment codes for the virus RNA-dependent RNA polymerase (L, ca 200 kDa) (19) and a small (11-kDa) RING finger protein (Z) (17).