The effect of oxygen admixtures on the electric field induced by an atmospheric pressure helium plasma jet
| Main Authors: | Lazarou, Constantinos, Anastassiou, Charalambos, Topala, Ionut, Chiper, Alina, Mihaila, Ilarion, Pohoata, Valey, Georghiou, George E. |
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| Format: | Proceeding poster eJournal |
| Terbitan: |
, 2019
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/3521707 |
Daftar Isi:
- Reactive oxygen and nitrogen species (RONS) play a central role in the immune system and on disease progression and therefore are important in the therapeutic abilities of the atmospheric pressure plasma jet (APPJ) [1]. In addition to RONS, the APPJ induces an electric field (IEF) on the biological cells. It can be inferred that it is the combination of IEF and RONS and not just RONS that gives the APPJ its unique therapeutic abilities, such as selectively treating cancer [2]. In the case of helium APPJ it was found that the addition of oxygen impurities allowed for more effective treatment of cancer cells [3]. Putting it all together, the hypothesis is that the addition of oxygen causes higher IEF on cancerous cells causing electroporation and the introduction of RONS in the cells causing apoptosis. In this abstract a two-dimensional axi-symmetric model is developed [4] for the description of a capillary helium plasma jet with and without the presence of oxygen admixtures and their interaction with a dielectric surface placed normal to the jet axis. The results in Figure 1 show that He/O2 plasma jets generates higher IEF in comparison to the pure He plasma jet. Furthermore, the peak of the IEF on the dielectric surface is on the axis of symmetry for He/O2 plasma jets and off the axis of symmetry for pure He plasma jet. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under agreement No. 810686. References [1] D. B. Graves, Phys. Plasmas, 21, 080901 (2014) [2] J. Van der Paal, C. Verheyen, E. C. Neyts and A. Bogaerts, Sci. Rep., 7, 39526 (2017) [3] S. J. Kim, T. H. Chung, S. H. Bae and S. H. Leem, Appl. Phys. Lett., 97, 023702 (2010) [4] C. Lazarou, C. Anastassiou, I. Topala, A. S. Chiper, I. Mihaila, V. Pohoata and G. E. Georghiou, Plasma Sources Sci. Technol., 27, 105007 (2018)
- International Workshop on Plasma for Cancer Treatment (IWPCT 2019), April 1-3, 2019 Antwerp, Belgium