Nephrogenic diabetes insipidus in a patient with lymphoma
| Main Authors: | Rollino Cristiana, Manuela Sandrone, Pagliaro Maria, Roccatello Dario |
|---|---|
| Format: | Article eJournal |
| Bahasa: | ang |
| Terbitan: |
, 2019
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/3519609 |
Daftar Isi:
- We present the case of a woman developing nephrogenic diabetes insipidus in the course of stage IVB T lymphoma with no involvement of the hypothalamus/pituitary area, but extensive involvement of both kidneys. A diagnosis of tubulopathy with acquired nephrogenic diabetes insipidus was made. Introduction Abnormal secretion or response to ADH (Anti Diuretic Hormone) is reported in cancer patients. Central diabetes insipidus may develop secondary to cancer invasion of one or more of the sites involved in ADH secretion: the hypothalamic osmoreceptors, the supraoptic or paraventricular nuclei, or the superior portion of the supraoptico hypophyseal tract [1]. Rarely nephrogenic diabetes insipidus may present as a paraneoplastic lesion [2]. We report the case of a patient who developed nephrogenic diabetes insipidus following an extensive invasion of the kidney tissue by lymphomatous cells in stage IVB T lymphoma.