Purification of further GS loop mutations of ALK2/ ACVR1 protein expressed in insect cells
| Main Authors: | Williams, Eleanor, Bullock, Alex |
|---|---|
| Format: | Article eJournal |
| Bahasa: | eng |
| Terbitan: |
, 2019
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/3453086 |
Daftar Isi:
- Further purification of three constructs of ALK2 protein containing different mutations within the GS loop as part of an ongoing investigation into the influence of the phosphorylation of ALK2 on it's overall activity. Proteins purified in vitro for future biophyiscal characterisation. You can read more over on Open Lab Notebooks.
- Funding Acknowledgment: The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.