CASE STUDY ON EWING SARCOMA
| Main Author: | Nadeem Khokhar, Ms. Hajra Sarwar, Mr. Muhammad Afzal |
|---|---|
| Format: | Article eJournal |
| Terbitan: |
, 2019
|
| Online Access: |
https://zenodo.org/record/3364662 |
Daftar Isi:
- Ewing’s sarcoma is the 2nd most common primary sacral tumor. Ewing’s sarcomas are rare, aggressive tumors with a tendency concerning recurrence subsequent resection and early metastasis. Although peak incidents are between the ages of 10 and 20 years, patients of younger or older age account for almost 30% of the cases. We report the case of a 37-year-old healthy male who presented with an 8-month history of pain in his right posterior thigh that was unable to be comforted by non-steroidal anti-inflammatory medicine and physical therapy. Magnetic resonance imaging shown an irregular right presacral mass and core needle biopsy shown a small, round blue cell neoplasm. Staging workup was normal and an open biopsy was positive for the ES translocation. The patient was treated with 5 cycles of vincristine, adriamycin and cytoxan with mesna rescue, alternating with ifosfamide and etoposide. 4 month post-treatment the patient presented with a recurrent tumor. This case emphasizes the importance of timely establishment of initial diagnosis, early metastasis in treatment responsive patients and under-utilization of positron emission tomography-computed tomography (PET-CT) during the treatment to detect sub-clinical metastasis. Doctor changed the chemotherapy medicines to cyclophosphamide and carboplatin after reoccurrence of tumor.