Cationic Quaternized Chitosan Nanoparticles for C-phycocyanin Delivery to Hela Cells
| Main Authors: | Yang, Peng, Li, Bing, Lv, Cong-Yi, Yin, Qi-Feng, Wang, Yu-Juan |
|---|---|
| Format: | Article eJournal |
| Bahasa: | eng |
| Terbitan: |
, 2015
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/3349007 |
Daftar Isi:
- In this study we synthesize C-PC/QAC nanoparticles using cationic quaternary ammonium chitosan (QAC) as substrate material loaded C-phycocyanin (C-PC) by ionic-gelation method. The prepared NPs was about 120nm size with spherical morphology, the entrapment efficient was 62%, and the drug-loading amount was 20%. The NPs exhibited a pH sensitive realease of C-PC in vitro. The drug-NPs were proved to be hemocompatible and safe. In conclusion, QAC increased bioavailability and anticancer property of C-PC.Read Complete Article at ijSciences: V4201509834 AND DOI: http://dx.doi.org/10.18483/ijSci.834