The body weight and serum lipid levels in ApoE-/- mice treated with or without NAC or LST

Main Authors: Yan Zhang, Zuyi Yuan
Format: info Image eJournal
Terbitan: , 2019
Online Access: https://zenodo.org/record/3334055
Daftar Isi:
  • Neither NAC nor LST changes the body weight and serum lipid levels of high-fat-fed ApoE-/- mice. ApoE-/- mice were fed with a chow diet or high fat diet and were oral administered with NAC (1mg/mL) or LST (10 mg/kg/day) for 16 weeks. A growth curves of body weight; B serum TG; C TC and D LDL-C levels in ApoE-/- mice. Plots are means ± SD.* p<0.05 and **P <0.01. Experiments were performed on male mice, n=8 per group. AS, atherosclerosis; Con, control; LDL-C, low density lipoprotein cholesterol; LST, losartan; NAC, N-Acetyl-L-cysteine; n.s. not significant; TC, total cholesterol; TG, triglyceride.