Secretory Breast Carcinoma: A Case Report With Literature Review
| Main Author: | S. Amouzoune , A. Belbachir , F. Boukis , S. Houari , A. Soumani , H. El Mansouri , N.I. Guennouni, H. Rais |
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| Format: | Article eJournal |
| Terbitan: |
, 2019
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/3239007 |
Daftar Isi:
- Secretory breast carcinoma (SBC) is a very rare tumor in adults with a very good prognosis after surgical treatment. We report the case of a 56-year-old patient presenting for a nodule of the superior left quadrant of the left breast that had been evolving for 5 months. A biopsy was performed and showed a poorly differentiated and infiltrating carcinoma. A complement by lumpectomy with lymphadenectomy was done and concluded a secretory carcinoma of the breast without lymph node metastasis. PAS staining and immunohistochemical study were performed and confirmed the diagnosis. SBC is a rare entity. The age of onset varies between 3 and 87 years with a mean age of 33 and 40 years. The common clinical sign is the progressive establishment of a mobile and well circumscribed mammary nodule. The presence of eosinophilic and mucoid secretory material intra- and extra-cellular is the main histological sign in CS that differentiates it from other histological types. In immunohistochemistry, these tumors strongly express PS100 with a triple negative molecular profile. The risk of local recurrence is usually minimal with a long survival despite lymph node metastases.