DESIGN, SYNTHESIS AND CHARACTERISATION OF SOME SEMICARBAZONE AND THIOSEMICARBAZONE DERIVED FROM 3-PHENYLQUINAZOLINE-2, 4(1H, 3H)-DIONE
| Main Author: | Ashok N. Patange*1, Ramesh G.Paloti2, Ramesh N.Zade3, Kushal M.Mude4 & Bhupesh M.Mude5 |
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| Format: | Article eJournal |
| Terbitan: |
, 2018
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/1211485 |
Daftar Isi:
- This paper presents the synthesis and characterizations of some semicarbazone and thiosemicarbazone derivatives of3-phenylquinazoline-2,4(1H,3H)-dione. All compounds reported here had been characterised by1H NMR and IR spectral studies and elemental analysis. semicarbazone and thiosemicarbazone derivatives of 3-phenylquinazoline-2,4(1H,3H)-dionewere prepared by treating mixture of phenyl isocyanates and anthanilic acid in ethanol to get 3-phenylquinazoline-2,4(1H,3H)-dionewhich will then condense with substituted4-chloro/bromo/iodoAcetophenones in ethanolto form the chalcones .this chalcones were treated with semicarbazide and thiosemicarbazide in ehanol to get semicarbazone and thiosemicarbazone derivatives of 3-phenylquinazoline-2,4(1H,3H)-dione to explore the biological activities and importance as ligands for various transition metal complexes.