PENGARUH PEMBERIAN METOCLOPRAMID 20mg/IV TERHADAP KEJADIAN RETENSI URINE PASCABEDAH DENGAN ANESTESI SPINAL PADA PEMBEDAHAN ORTOPEDI EKSTREMITAS BAWAH
Main Author: | Side, Arifuddin |
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Format: | Thesis NonPeerReviewed Book Image |
Bahasa: | ind |
Terbitan: |
, 2013
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Subjects: | |
Online Access: |
http://repository.unhas.ac.id/id/eprint/7980/ |
Daftar Isi:
- ARIFUDDIN SIDE. Reduction in Spinal-Induced Postoperative Urine Retention with Metoclopramid in Lower Extremity Orthopedic Surgery: A Randomized Double Blind, Placebo-Controlled Study (Supervised by Wahyudi). Background : Post operative urine retention(POUR) is frequent complication associated spinal anaesthesia by blocked parasimpathies outonomic nervous sistem in spinal cord S2-S4. Result not realesed asetilcholine post synaptic. Smooth muscle of bladder fail to contraction Objective : We evaluated the effect of metoclopramide as a parasympathomimetic that inhibited cholinesterase enzyme (PCHE and ACHE) in vitro and in vivo to post operative urine retention induced spinal anaesthesia in inferior extremity orthopedic electif surgery. Methode : Fourty participants scheduled for inferior extremity orthopedic electif surgery randomly into two groups. Before induction of spinal anaesthesia Group M (n = 20) received intravenous metoclopramide 20 mg,; Group N (n = 20) received normal saline. Time first micturation and POUR were assessed. Result : Time for first micturation significant shorter in Group M 5,41 + 0,56 and 9,93 + 0,65 in Group N (P = 0,000), and had significantly lower incidencesof POUR in Group M (P = 0,013) Conclusion : Metoclopramide 20 mg given intravenously before spinal anaesthesia reduced POUR. Time for first micturation also lower in inferior extremity orthopedic electif surgery. Keywords : Metoclopramide, spinal anaesthesia, aseticholine, post operative urine retention, inferior extremity orthopedic surgery