Synthesis of several 2-(5-chloro-3-methyl-1-(pyridin-2-yl) pyrazolidin-4-yl)-3- substitutedphenylthiazolidin-4-ones as prospective antimicrobial agents

Main Author: Hament Panwar
Format: Article Journal
Terbitan: , 2014
Subjects:
Online Access: https://zenodo.org/record/913109
Daftar Isi:
  • Several 2-(5-chloro-3-methyl-1-(pyridin-2-yl) pyrazolidin-4-yl)-3- substitutedphenylthiazolidin-4-one (4a-f) have been synthesized by conventional synthesis methodology. The synthesized derivatives were characterized by IR, 1H-NMR, Mass and elemental analysis (C, H, N) . Furthermore the synthesized 2-(5-chloro-3-methyl-1-(pyridin-2-yl) pyrazolidin-4-yl)-3- substitutedphenylthiazolidin-4-one (4a-f) were tested for antimicrobial activities. The compound 4c displayed significant biological activities among the all tested derivatives.