Studies in the Synthesis of Quinoline Derivatives Part IV : Synthesis of Furoquinolines

Main Authors: R. J. Chudgar, K. N. Trivedi
Format: Article Journal
Bahasa: eng
Terbitan: , 1971
Subjects:
Online Access: https://zenodo.org/record/6446328
Daftar Isi:
  • 2-Methyl-3-formyl-4-quinolinol (Ia) on condensation with ethyl bromoacetate gave (Ila), but on hydrolysis original quinoline derivative was obtained back. (Ia) on co,ndensation with ethyl bromomalonate gave 4-methyl-2-carboethoxymethoxy qumohne (IVa), which on hydrolysis and subsequent decarboxylation furnished 4-methyl-furo(3,2-c)quinolme (IVc). Similar condensation of 2,8-dimethyl-3-formyl-4- quinolinol (lb) and 6-methoxy-2-methyl-3-formyl-4-quinolinol (Ic) w1th ethyl bromomalonate gave (IVd) and (IVe) respectively