Synthesis of Some 2,6-Diamino-9-arylpurines, 2,6-Diamino-9- aryl-8-azapurines and Some Related 5-Phenylazopyrimidines
| Main Authors: | D. SEN, PURNENDU SENGUPTA |
|---|---|
| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 1973
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/6420228 |
Daftar Isi:
- Department of Applied Chemistry, University College of Science and Technology, Calcutta-9 Manuscript received 4 August 1972; accepted 17 February 1973 Synthesis of some 2,6-diamino-9-arylpurines,2,6mino-9-ary1-8-azapurines and 2,4-diamino6-arylamino-5-phenylazopyrirnidines have been reported. 9-Arylpurines were prepared by the cyclization with formamide of appropriate 6-arylamino-2,4,5-triaminopyrimidine bisulphite. The 9-aryl-8-azapurines were prepared by the cyclization of the above 2,4,5-triasninopyrimidine bisulphites with nitrous acid. The 6-ary/amino-2,4,5-triaminopyrimidine bisulphites were obtained by the reduction of the 2,4-diamino-5-nitroso-6-arylarninopyrimidines with sodium hydrosulphite. The 5-phenylazopyrimidines were synthesized by the reaction of appropriate 2,4-diamino-6-arylaminopyrimidines with benzenediazonium chloride. The assignment of structures of these 9- arylpurines and 9-aryl-8-azapurines were based upon their lack of acidic character.